Description

Ismo Retard Tablet ER is an extended-release formulation of Isosorbide Mononitrate, a nitrate medicine used for the prevention and long-term treatment of angina pectoris (chest pain caused by reduced blood flow to the heart). Its sustained release action ensures a steady therapeutic effect over an extended period, reducing the frequency of angina attacks and improving heart efficiency. Unlike fast-acting nitroglycerin tablets, it is not intended for immediate relief of acute angina episodes but is instead prescribed for ongoing management.

Uses

Prevention of stable angina pectoris
Long-term treatment of coronary artery disease (CAD)
Adjunct therapy in congestive heart failure (CHF) (as directed by a doctor)
Improves exercise tolerance in cardiac patients

How It Works

Isosorbide Mononitrate releases nitric oxide, a natural vasodilator, which relaxes vascular smooth muscle. This leads to dilation of veins and arteries, reducing the preload (venous return) and afterload (arterial resistance) on the heart. By decreasing myocardial oxygen demand and improving coronary blood flow, it helps prevent angina attacks and enhances heart performance.

The extended-release (ER) design ensures a slow and consistent release of medicine, providing sustained protection against angina throughout the day.

Benefits

Provides long-lasting prevention of angina attacks
Reduces frequency and severity of chest pain
Improves blood and oxygen supply to the heart muscle
Enhances exercise capacity and daily activity tolerance
Convenient once-daily dosing due to extended release action

Directions for Use

Take orally with water, preferably at the same time daily.
Swallow whole; do not crush or chew the tablet, as it is extended-release.
Should be taken as prescribed by your doctor for effective prevention.
Not suitable for acute angina relief (sublingual nitroglycerin is used in emergencies).

Safety Information

Use strictly under medical advice.
Common side effects: headache, dizziness, flushing, nausea, low blood pressure.
Avoid alcohol as it may increase the risk of dizziness and fainting.
Not to be taken with phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil) due to risk of severe hypotension.
Caution required in patients with low blood pressure, recent myocardial infarction, hypertrophic cardiomyopathy, or severe anemia.
Pregnant and breastfeeding women should use only if recommended by a doctor.