Description

Gabaneuron NT 100 Tablet is a combination medicine used primarily to manage neuropathic pain (nerve pain) caused by conditions like diabetic neuropathy, post-herpetic neuralgia, sciatica, or spinal cord injuries. It contains Gabapentin, an antiepileptic drug with pain-relieving properties, and Nortriptyline, a tricyclic antidepressant (TCA) that helps control pain signals and improves mood.

This combination is especially useful in patients who suffer from chronic nerve pain associated with anxiety, depression, or sleep disturbances.

Uses / Indications

Neuropathic pain (nerve pain due to diabetes, shingles, or injuries)
Peripheral neuropathy
Postherpetic neuralgia (nerve pain after shingles)
Fibromyalgia (widespread muscle pain with fatigue and sleep problems)
Chronic nerve pain resistant to standard painkillers
Adjunct treatment in seizure disorders (in some cases)

How It Works (Mechanism of Action)

Gabapentin (100 mg):
- Modulates overactive nerve cells by binding to voltage-gated calcium channels.
- Reduces excessive pain signal transmission in the brain and spinal cord.
- Provides both analgesic and anticonvulsant effects.
Nortriptyline (10 mg):
- A tricyclic antidepressant (TCA).
- Increases levels of serotonin and norepinephrine in the brain.
- Reduces nerve pain perception and improves mood, sleep, and overall quality of life.

Together, they provide pain relief, mood stabilization, and improved nerve function.

Dosage & Administration

Typical dose: One tablet once or twice daily, or as prescribed.
Should be taken with or without food, swallowed whole with water.
Doctors usually start at a low dose (100 mg Gabapentin + 10 mg Nortriptyline) and adjust gradually.
Must be taken regularly for best results.
Do not stop suddenly, as abrupt withdrawal can worsen pain or cause withdrawal effects.

Side Effects

Common:

Drowsiness, dizziness, sleepiness
Dry mouth, constipation
Blurred vision
Weight gain, swelling in hands/feet
Tiredness, low energy

Less common but serious:

Mood changes, depression, suicidal thoughts
Irregular heartbeat or palpitations
Urinary retention or difficulty passing urine
Severe allergic reactions (rash, itching, swelling)
Confusion or difficulty concentrating (especially in elderly patients)

Precautions & Warnings

May cause drowsiness → avoid driving, operating machinery, or risky activities.
Avoid alcohol, as it increases sedation and side effects.
Should be used cautiously in patients with heart disease, kidney problems, glaucoma, or psychiatric disorders.
Not recommended in children unless prescribed.
Pregnant and breastfeeding women should take only under strict medical supervision.
Dose adjustment may be required in elderly patients.

Summary

Gabaneuron NT 100 Tablet (Gabapentin 100 mg + Nortriptyline 10 mg) is an effective treatment for neuropathic pain, fibromyalgia, and nerve-related chronic pain. It not only relieves pain but also helps with sleep and mood stabilization, making it a good option for patients with both pain and associated depression or anxiety. However, it can cause drowsiness, dry mouth, constipation, and mood changes, so close medical supervision is essential.

Gabaneuron NT 100 Tablet