Mero 125mg Injection

Description

Mero 125mg Injection is a broad-spectrum carbapenem antibiotic used to treat serious bacterial infections. It contains Meropenem (125mg), which belongs to the beta-lactam class of antibiotics. Meropenem works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death.

It is effective against a wide range of Gram-positive, Gram-negative, and anaerobic bacteria, including strains that are resistant to other antibiotics.

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Uses / Indications

• Severe respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections (UTIs)

• Intra-abdominal infections

• Skin and soft tissue infections

• Septicemia (bloodstream infections)

• Meningitis

• Infections caused by multi-drug resistant Gram-negative bacteria

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How It Works

• Meropenem binds to penicillin-binding proteins (PBPs) in bacterial cell walls.

• This disrupts cell wall synthesis, causing bacterial lysis and death.

• It is resistant to most beta-lactamases, making it effective against resistant bacteria.

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Dosage & Administration

• Administered intravenously (IV) or intramuscularly (IM) under medical supervision.

• Adult dosage is usually 125mg–1g every 8 hours, depending on infection severity.

• Pediatric dosage is weight-based.

• Infuse over 15–30 minutes for IV administration.

• Duration of therapy depends on infection type and response.

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Side Effects

Common:

• Nausea, vomiting, diarrhea

• Headache

• Pain or redness at the injection site

Less Common / Rare:

• Rash, itching, or mild allergic reactions

• Elevated liver enzymes

Serious (rare):

• Severe allergic reactions (anaphylaxis)

• Seizures (especially in patients with CNS disorders or renal impairment)

• Clostridium difficile-associated diarrhea

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Precautions & Warnings

• Avoid in patients with known hypersensitivity to carbapenems or beta-lactams.

• Use cautiously in renal impairment; dosage adjustment may be required.

• Monitor for allergic reactions and gastrointestinal disturbances.

• Complete the full prescribed course to prevent resistant infections.

• Not effective against viral infections.

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Summary

Mero 125mg Injection (Meropenem 125mg) is a broad-spectrum carbapenem antibiotic for serious Gram-positive, Gram-negative, and anaerobic infections. It should be administered under strict medical supervision, with attention to renal function and allergy history, ensuring the full course is completed for optimal efficacy.