Description
Omcef 100mg/100mg Tablet DT is a dispersible combination antibiotic containing Cefixime, a third-generation cephalosporin, and Ofloxacin, a fluoroquinolone. It is used to treat bacterial infections, particularly those resistant to single antibiotics. Being a DT (dispersible tablet), it can be dissolved in water for easier administration, especially in children and patients who have difficulty swallowing tablets.
Uses
-
Respiratory tract infections – bronchitis, pneumonia, sinusitis, tonsillitis
-
Urinary tract infections (UTIs)
-
Gastrointestinal infections – enteric fever, gastroenteritis
-
Skin and soft tissue infections
-
Ear infections (otitis media)
-
Bone and joint infections
-
Other bacterial infections resistant to monotherapy
How It Works
-
Cefixime (100mg): Inhibits bacterial cell wall synthesis, causing bacterial death.
-
Ofloxacin (100mg): Inhibits bacterial DNA gyrase and topoisomerase IV, preventing bacterial replication.
The combination provides broader antibacterial coverage than either drug alone.
Side Effects
Common:
-
Nausea, vomiting, diarrhea
-
Stomach discomfort or abdominal pain
-
Headache, dizziness
-
Mild skin rash
Serious (rare):
-
Severe allergic reactions (swelling, difficulty breathing, anaphylaxis)
-
Tendonitis or tendon rupture (linked to Ofloxacin)
-
Liver enzyme abnormalities
-
Blood disorders (low platelets, anemia, leukopenia)
-
Clostridium difficile-associated diarrhea
Precautions
-
Avoid in patients allergic to cephalosporins or fluoroquinolones
-
Use with caution in renal or hepatic impairment (dose adjustment may be required)
-
Not recommended in pregnancy and breastfeeding unless prescribed
-
Avoid excessive sun exposure due to photosensitivity risk (from Ofloxacin)
-
Not for use in children under a certain age unless specifically prescribed
Administration
-
Dispersible tablet: Can be dissolved in a small amount of water before intake
-
Usually taken twice daily or as prescribed by a doctor
-
Complete the full course to prevent antibiotic resistance
Leave a Reply