Description

Canditral SB 130 Capsule is a super bioavailable formulation of Itraconazole (130mg), designed to improve absorption and therapeutic efficacy compared to conventional itraconazole capsules. This means lower inter-patient variability, better systemic availability, and consistent antifungal activity, even at lower doses.

Itraconazole works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This disrupts cell membrane integrity, leading to fungal cell death. The SB (Super Bioavailable) technology makes it a preferred choice for systemic and resistant fungal infections, where precise drug delivery is crucial.

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Uses

• Onychomycosis (fungal nail infections requiring long-term therapy)

• Refractory dermatophytosis (skin infections resistant to standard treatment)

• Oropharyngeal & esophageal candidiasis (mouth and throat fungal infections)

• Vulvovaginal candidiasis (recurrent yeast infections)

• Systemic mycoses including:

  • Aspergillosis

  • Histoplasmosis

  • Blastomycosis

  • Sporotrichosis

• Alternative therapy for patients where standard itraconazole absorption is unreliable

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Dosage & Directions for Use

• Usual adult dose: 130 mg once or twice daily, depending on infection severity.

• Should be taken immediately after meals for enhanced absorption.

• Duration varies by infection type:

  • Skin infections: 1–4 weeks

  • Nail infections: 3–6 months

  • Systemic infections: several weeks to months, as per doctor’s guidance

• Always complete the full course; stopping early can lead to relapse.

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Possible Side Effects

Common side effects:

• Nausea, vomiting, abdominal pain, indigestion

• Headache, dizziness

• Mild rash or skin irritation

• Fatigue

Serious but rare:

• Hepatotoxicity (jaundice, dark urine, persistent fatigue)

• Cardiac issues (heart failure, swelling of legs, breathlessness)

• Severe allergic reactions (rash, itching, swelling, breathing difficulty)

⚠️ Use cautiously in patients with liver, kidney, or heart conditions. Regular monitoring may be required during prolonged treatment.