Category: Medicines

Uses:
Mesacol Enema is used for the treatment of ulcerative colitis, especially when inflammation affects the lower colon and rectum. Mesalazine (5-aminosalicylic acid) helps reduce inflammation, control rectal bleeding, and relieve associated abdominal discomfort and diarrhea.

Dosage:
The dosage is prescribed by a doctor. Typically, one enema once daily, preferably at bedtime, or as directed by the healthcare professional.

How to Use:

• Shake the enema well before use.

• Remove the cap and gently insert the nozzle into the rectum.

• Slowly squeeze the contents into the rectum.

• Remain lying down for 10–15 minutes to ensure absorption.

• Wash hands thoroughly after administration.

Precautions:

• Inform your doctor if you have kidney, liver, or heart problems.

• Do not use if allergic to Mesalazine or related drugs.

• Consult your doctor if symptoms persist or worsen.

• Use during pregnancy or breastfeeding only if clearly prescribed.

Side Effects:

• Common: Mild rectal irritation, nausea

• Moderate: Abdominal discomfort, diarrhea

• Rare: Severe allergic reactions, kidney or liver issues

Storage:

• Store in a cool, dry place below 30°C.

• Keep the enema in its original packaging until use.

• Keep out of reach of children.

Uses:
Mesacol OD Tablet PR is used for the treatment and maintenance of remission in ulcerative colitis and other inflammatory bowel diseases. Mesalazine (5-aminosalicylic acid) helps reduce inflammation in the intestines, relieve abdominal pain, diarrhea, and rectal bleeding. The PR (prolonged-release) formulation ensures a steady release of medication for once-daily dosing.

Dosage:
The dosage is prescribed by a doctor based on the severity of the condition. Typically, one tablet once daily or as directed by the healthcare professional.

How to Use:

• Take orally with water, preferably after meals.

• Swallow the tablet whole; do not crush or chew, as it is a prolonged-release formulation.

• Take at the same time each day for consistent effect.

Precautions:

• Inform your doctor if you have kidney, liver, or heart problems.

• Do not use if allergic to Mesalazine or related drugs.

• Monitor for unusual symptoms like persistent diarrhea, severe abdominal pain, or blood in urine.

• Use during pregnancy or breastfeeding only if prescribed.

Side Effects:

• Common: Nausea, mild headache, abdominal discomfort

• Moderate: Diarrhea, flatulence, rash

• Rare: Severe allergic reactions, kidney or liver complications, pancreatitis

Storage:

• Store in a cool, dry place below 30°C.

• Protect from light and moisture.

• Keep out of reach of children.

METADON 25 XL is a prolonged-release beta-blocker tablet designed for the management of cardiovascular disorders. Each film-coated Alu/Alu blister tablet delivers a controlled dose of Metoprolol Succinate, equivalent to 25 mg of Metoprolol Tartrate, ensuring stable blood levels and once-daily convenience.

How it Works

Metoprolol is a selective beta-1 adrenergic blocker that slows the heart rate, reduces the heart’s workload, and lowers blood pressure. It acts by blocking the action of specific natural chemicals (epinephrine) on the heart and blood vessels, resulting in decreased cardiac output and oxygen demand.

Main Uses

• Treatment of hypertension (high blood pressure)

• Management of angina pectoris (chest pain due to heart disease)

• Control of irregular heart rhythms (arrhythmias, including atrial fibrillation)

• Prevention of heart attacks, strokes, and migraines

Key Benefits

• Reduces risk of stroke, heart attack, and cardiovascular complications in hypertensive patients

• Prevents and lessens frequency of angina attacks

• Stabilizes irregular heartbeats, improving overall cardiac function

• Prolonged-release formulation allows once-daily dosing and sustained therapeutic effect

Dosage & Administration

• Taken orally once daily, preferably at the same time each day, with or without food

• Strictly follow medical advice regarding dose adjustments or discontinuation

• Regular monitoring of blood pressure and heart rate is recommended during therapy

Safety & Precautions

• Not suitable for patients with severe bradycardia, heart block, pronounced heart failure, or shock

• Common side effects: dizziness, tiredness, headache, slow heart rate, nausea, diarrhea, depression, and rash; may cause low blood pressure or breathlessness in some individuals

• Use with caution in patients with liver problems, or in pregnancy or lactation (consult doctor)

• Avoid abrupt discontinuation to prevent rebound high blood pressure or heart issues; consult a physician for dose tapering if needed

• Alcohol may increase side effects such as dizziness; best avoided

METADON 50 AM is a bilayered, prolonged-release antihypertensive tablet delivered in Alu/Alu blister packs. This synergistic combination therapy effectively lowers blood pressure and heart rate, while providing relief from angina (chest pain) and cardiovascular risks associated with high blood pressure.

How it Works

• Metoprolol Succinate is a selective beta-blocker that decreases heart rate and contractility, lowering cardiac workload and blood pressure.

• Amlodipine Besylate is a calcium channel blocker that relaxes and dilates blood vessels, resulting in reduced resistance, easier blood flow, and diminished heart stress.

• Both components work together to relieve cardiac symptoms, prevent hypertension-related complications, and improve exercise tolerance.

Main Uses

• Long-term management of hypertension (high blood pressure)

• Relief and prevention of angina pectoris (chest pain due to heart disease)

• Improves heart function and reduces the risk of strokes, heart attacks, and organ damage

Key Benefits

• Dual-action blood pressure control and cardiac protection in a single daily tablet

• Reduces risk of major heart, kidney, and vascular complications

• Proven safety and efficacy in routine cardiac care, with improved patient adherence due to convenience

Dosage & Administration

• Take once daily, with or without food, at the same time for best results; swallow whole and do not crush or chew

• Dosage and duration individualized as per physician’s prescription and patient clinical status

• Regular monitoring of blood pressure, heart rate, kidney, and liver function recommended

Safety & Precautions

• Not suitable for patients with severe heart failure, bradycardia, heart block, significant liver/kidney disease, or asthma

• Common side effects: dizziness, headache, slow heart rate, fatigue, ankle swelling, constipation, sleepiness, depression, rash

• Avoid abrupt discontinuation; could trigger rebound hypertension or heart events

• Use with medical guidance in pregnancy, breastfeeding, and older adults; consult doctor before changing dose or frequency

Methimercazole 10 Tablet is a prescription medication containing Methimazole 10 mg, an antithyroid agent used primarily in the treatment of hyperthyroidism and related thyroid disorders. Manufactured by Abbott, this tablet is formulated to regulate excessive thyroid hormone production, helping restore normal metabolic function and reduce symptoms associated with an overactive thyroid.

Methimazole belongs to the thionamide class of medications and works by inhibiting the synthesis of thyroid hormones (T3 and T4). By blocking the thyroid gland’s ability to produce excess hormones, Methimercazole helps normalize hormone levels, alleviating the clinical manifestations of hyperthyroidism such as weight loss, rapid heartbeat, anxiety, and tremors.

Therapeutic Uses:

1. Graves’ Disease: Management of hyperthyroidism caused by autoimmune stimulation of the thyroid.

2. Toxic Multinodular Goiter: Helps control excessive hormone production in nodular thyroid conditions.

3. Thyroid Storm Prevention: Used as part of the therapy in acute thyrotoxic crises under medical supervision.

4. Pre-Surgical Preparation: Helps stabilize thyroid hormone levels prior to thyroid surgery.

Mechanism of Action:
Methimazole acts by inhibiting thyroid peroxidase, an enzyme involved in the synthesis of thyroid hormones T3 (triiodothyronine) and T4 (thyroxine). This reduces the production of excess hormones, leading to improved metabolic balance and alleviation of hyperthyroid symptoms.

Dosage & Administration:

• Methimercazole 10 Tablet should be taken exactly as prescribed by a healthcare professional.

• It is intended for oral use and should be swallowed with water, with or without food.

• Dosage may vary depending on the patient’s thyroid hormone levels, severity of hyperthyroidism, and clinical response.

• Regular monitoring of thyroid function tests (T3, T4, TSH) is essential to adjust dosage appropriately.

• Abrupt discontinuation is not recommended without consulting a doctor, as it may lead to recurrence of hyperthyroid symptoms.

Safety Information & Precautions:

• Methimercazole is prescription-only and should be used under medical supervision.

• Patients should inform their doctor about any history of:

  • Liver disease or impaired liver function

  • Blood disorders (e.g., anemia, leukopenia)

  • Allergic reactions to thionamides

• Common side effects may include:

  • Nausea, vomiting, or abdominal discomfort

  • Skin rash or itching

  • Mild headache or dizziness

• Serious but rare side effects include:

  • Agranulocytosis (low white blood cell count)

  • Severe liver toxicity

  • Fever, sore throat, or unexplained infections

• Patients should report any unusual symptoms to their doctor immediately.

Packaging:
Methimercazole 10 Tablet is typically available in blister strips or bottles, designed for convenient daily administration.

Storage:

• Store in a cool, dry place below 25°C (77°F)

• Protect from direct sunlight, moisture, and heat

• Keep out of reach of children

• Do not use after the expiration date on the packaging

Key Benefits:

• Effectively reduces excessive thyroid hormone production

• Helps manage symptoms of hyperthyroidism such as rapid heartbeat, anxiety, and weight loss

• Supports stabilization of thyroid function before surgery or radioactive iodine therapy

• Manufactured by Abbott, ensuring quality, efficacy, and safety

• Oral tablet formulation allows easy daily dosing and monitoring

Conclusion:
Methimercazole 10 Tablet is a trusted and effective treatment for hyperthyroidism and related thyroid disorders. By controlling excess thyroid hormone synthesis, it helps restore metabolic balance, improve clinical symptoms, and enhance patient quality of life. When used under medical supervision with regular thyroid function monitoring, Methimercazole 10 Tablet provides safe, reliable, and long-term management of hyperthyroid conditions.