CERBILEP-25

Description

Cerbilep-25 Tablet contains topiramate, an antiepileptic drug (AED) used primarily to treat epilepsy (seizures) and for migraine prevention. It can be used both as single therapy and as add-on (adjunctive) therapy in specific seizure types and headache disorders.

Uses / Indications

• Epilepsy (seizures):

  • Monotherapy or adjunctive therapy for partial-onset seizures and primary generalized tonic-clonic seizures in adults and children (age 2+)

  • Adjunctive treatment of seizures associated with Lennox-Gastaut syndrome (a severe childhood epilepsy)

• Migraine prophylaxis: Prevention of migraine headaches in adults and adolescents; it does not treat acute migraine pain but reduces attack frequency and severity

• Other uses (off-label): Sometimes used for neuropathic pain, mood stabilization (bipolar disorder), chronic weight management, binge eating disorders, and some other neurological conditions as directed by a physician.

How it Works / Key Benefits

• Blocks abnormal electrical activity in the brain by inhibiting sodium channels, enhancing GABA activity, antagonizing AMPA/kainate glutamate receptors, and inhibiting carbonic anhydrase.

• This suppresses seizures and helps prevent the overexcitation that can trigger migraines.

Dosage & Administration

• Dose and titration depend on age, indication, whether used alone or with other drugs, and clinical response; usually started low (e.g., 25 mg/day) and increased gradually.

• Take as prescribed—may be with or without food; drink plenty of fluids to reduce risk of kidney stones.

Safety & Side Effects

• Common: Tiredness, dizziness, drowsiness, loss of coordination, tingling (hands/feet), weight loss, decreased appetite, bad taste, diarrhea.

• Serious/Rare: Speech or vision changes, confusion, mood changes, kidney stones, metabolic acidosis, decreased sweating—report promptly to your doctor.

• Avoid abrupt discontinuation; always taper per physician guidance to prevent withdrawal seizures.

• Caution in pregnancy (potential birth defects), kidney stones history, metabolic disorders, and when taking other CNS depressants.

Note:
Cerbilep-25 is only to be used under medical supervision with periodic review. Routine blood tests and monitoring are recommended for long-term use.