Depakote XR 500 Tablet

Description

Depakote XR 500 Tablet is a prescription medicine marketed by Sanofi India Ltd. It contains Divalproex (500mg) in an extended-release (XR) formulation, which allows the drug to release slowly over time, providing steady blood levels and convenient once-daily dosing for many patients.

It is commonly prescribed for the treatment of epilepsy (seizure disorders), bipolar disorder (manic depression), and for the prevention of migraine headaches. Divalproex works by stabilizing electrical activity in the brain and balancing neurotransmitters, which helps reduce seizures, control mood swings, and lower migraine frequency.

Uses

• Epilepsy (Seizures): Controls both generalized and partial seizures

• Bipolar Disorder: Helps prevent mood episodes such as mania and depression

• Migraine Prevention: Reduces frequency, severity, and intensity of migraine attacks

Dosage

• Must be taken exactly as prescribed by the doctor

• Extended-release tablets should be swallowed whole, not crushed or chewed

• Usually taken once daily with food to reduce stomach irritation

• Dose depends on age, medical condition, and response to treatment

Side Effects

• Nausea, vomiting, stomach upset

• Drowsiness, dizziness, tremors

• Weight gain or loss

• Hair thinning (temporary in some cases)

• Rare but serious: liver problems, pancreatitis, low platelet count

Precautions

• Requires regular liver function, kidney function, and blood monitoring

• Avoid alcohol, as it may increase drowsiness and side effects

• Not recommended in pregnancy unless clearly necessary (may harm the baby)

• Use with caution in patients with a history of liver disease, pancreas issues, or bleeding problems

• Inform the doctor about all other medicines being used to prevent drug interactions