Depotex 125mg Injection

Description

Depotex 125mg Injection contains Methylprednisolone (125mg), a corticosteroid medicine used to treat inflammation, allergic reactions, and autoimmune disorders. It works by suppressing the immune system’s overactive response, thereby reducing swelling, redness, and pain in affected areas.

This injection provides rapid and long-lasting relief from inflammatory and allergic conditions affecting the joints, lungs, skin, and other organs. It is often used when oral corticosteroids are not suitable or when a faster therapeutic effect is needed.

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Uses of Depotex 125mg Injection

Depotex 125mg Injection is prescribed for a wide range of inflammatory and autoimmune conditions, including:

• Allergic disorders: Severe asthma, allergic rhinitis, drug or food allergies

• Rheumatic and joint disorders: Rheumatoid arthritis, osteoarthritis, gouty arthritis

• Skin diseases: Psoriasis, eczema, dermatitis, and lupus erythematosus

• Respiratory conditions: COPD (Chronic Obstructive Pulmonary Disease), severe asthma attacks

• Autoimmune disorders: Systemic lupus erythematosus (SLE), multiple sclerosis flare-ups

• Severe inflammation: Bursitis, tendonitis, and acute joint inflammation

• Adrenal insufficiency: When the body does not produce enough natural steroids

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How It Works

Methylprednisolone is a synthetic glucocorticoid that mimics the action of natural hormones produced by the adrenal glands. It works by:

• Inhibiting the release of inflammatory substances, such as prostaglandins and leukotrienes

• Suppressing immune system activity, preventing tissue damage caused by inflammation

• Reducing capillary permeability, thus minimizing swelling and redness

This mechanism helps control the symptoms of inflammation and allergic reactions effectively.

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Dosage and Administration

• The dosage of Depotex 125mg Injection depends on the type and severity of the condition being treated.

• It is administered intravenously (IV) or intramuscularly (IM) by a qualified healthcare professional.

• The duration and frequency of treatment are determined by the doctor based on patient response.

• Do not self-administer this injection.

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Side Effects

Like all corticosteroid medicines, Depotex 125mg Injection may cause some side effects, especially with long-term use. Common side effects include:

• Headache or dizziness

• Fluid retention or swelling

• Increased appetite and weight gain

• Mood changes, irritability, or insomnia

• Elevated blood sugar levels

• Stomach upset or nausea

• Increased risk of infection

• Muscle weakness or bone thinning (with prolonged use)

Contact your doctor immediately if you notice vision changes, severe mood swings, persistent infections, or unusual swelling.

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Precautions

• Inform your doctor if you have diabetes, high blood pressure, heart disease, or liver/kidney disorders.

• Avoid receiving live vaccines during corticosteroid treatment, as your immune system may be weakened.

• Use cautiously in pregnant or breastfeeding women — only if clearly needed and prescribed by a doctor.

• Sudden discontinuation may lead to withdrawal symptoms such as fatigue, low blood pressure, or joint pain — taper gradually under medical supervision.

• Avoid alcohol and smoking, as they can increase the risk of stomach irritation and bone loss.

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Drug Interactions

Depotex 125mg Injection may interact with the following medications:

• Anticoagulants (e.g., Warfarin)

• NSAIDs (e.g., Ibuprofen, Diclofenac)

• Antidiabetic medications

• Vaccines (especially live vaccines)

• Antifungal drugs (e.g., Ketoconazole)

• Antibiotics like Rifampicin

• Diuretics (water pills) — may increase potassium loss

Always inform your doctor about all medicines and supplements you are taking.

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Storage Instructions

• Store below 25°C, protected from light and moisture.

• Do not freeze.

• Keep out of reach of children.

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Key Benefits of Depotex 125mg Injection

• Provides fast relief from inflammation and allergic symptoms

• Helps control severe autoimmune and inflammatory conditions

• Reduces pain, swelling, and stiffness effectively

• Suitable for use when oral corticosteroids are not possible

• Offers rapid symptom improvement in acute conditions