Doxomax OD Tablet

Description

Doxomax OD Tablet is a long-acting bronchodilator used for the management of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It contains Doxofylline, a methylxanthine derivative, which helps relax the smooth muscles of the airways, making breathing easier. Unlike the older drug theophylline, Doxofylline has fewer cardiac and central nervous system side effects, making it a safer option for long-term use in respiratory diseases.

This medicine is generally prescribed to reduce wheezing, breathlessness, chest tightness, and other breathing difficulties caused by airway obstruction. It helps improve lung function, decreases the frequency of asthma attacks, and enhances the quality of life in patients suffering from chronic respiratory illnesses.

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Uses / Indications

• Asthma (prevention and management of acute and chronic attacks)

• Chronic Obstructive Pulmonary Disease (COPD)

• Bronchitis with airway obstruction

• Pulmonary diseases associated with difficulty in breathing and wheezing

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How It Works (Mechanism of Action)

• Doxofylline inhibits the enzyme phosphodiesterase (PDE) in the lungs.

• This increases cyclic AMP (cAMP) levels, which relaxes bronchial smooth muscles.

• Results in bronchodilation, improved airflow, and reduced breathing difficulties.

• Unlike theophylline, it has minimal effects on the heart and brain, thus reducing risks of arrhythmias and nervous system stimulation.

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Dosage & Administration

• Usual adult dose: One tablet (650 mg) once daily, or as prescribed by the physician.

• Should be swallowed whole with water, preferably after food.

• Do not crush or chew the tablet, as it is formulated for controlled release (OD = Once Daily).

• Dosage may vary depending on patient’s age, weight, and severity of disease.

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Side Effects

Doxomax OD Tablet is generally well tolerated, but some patients may experience:

• Nausea or vomiting

• Stomach upset or gastritis

• Headache or dizziness

• Insomnia (trouble sleeping)

• Increased heart rate (palpitations) – less common than with theophylline

• Rare: allergic reactions such as rash, itching, swelling

Seek immediate medical attention if severe chest pain, irregular heartbeat, or persistent vomiting occurs.

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Precautions & Warnings

• Use only under medical supervision.

• Caution in patients with heart disease, liver or kidney impairment, thyroid disorders, epilepsy, or high blood pressure.

• Avoid alcohol while taking this medicine.

• Inform your doctor about all other medications, as Doxofylline may interact with certain antibiotics, anticonvulsants, and other bronchodilators.

• Not recommended for children unless specifically prescribed.

• Pregnant and breastfeeding women should take only if clearly advised by the doctor.

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Summary

Doxomax OD Tablet (Doxofylline 650 mg) is a safe and effective bronchodilator used in the management of asthma and COPD. It works by relaxing the airway muscles, improving breathing, and reducing the frequency of attacks. With fewer cardiac and nervous system side effects compared to older methylxanthines, it is well suited for long-term therapy in chronic respiratory diseases.