ISOMIN 20

Description

Isomin 20 Tablet is a vasodilator medicine manufactured by Cipla Ltd, containing Isosorbide Mononitrate 20mg as its active ingredient. It is primarily used in the prevention and long-term management of angina pectoris (chest pain caused by reduced blood flow and oxygen supply to the heart muscle). Unlike quick-relief medicines used during an angina attack, Isomin 20 is intended for maintenance therapy to reduce the frequency and severity of angina episodes.

How It Works:
Isosorbide Mononitrate belongs to the class of organic nitrates. After administration, it is converted to nitric oxide (NO) in the body, which causes relaxation of smooth muscles in blood vessels. This results in:

• Dilation of veins (reducing the amount of blood returning to the heart → decreased preload)

• Dilation of arteries (lowering resistance against which the heart pumps → decreased afterload)

• Improved oxygen supply to the heart muscle

Together, these effects reduce the heart’s workload and oxygen demand, preventing angina attacks.

Uses of Isomin 20 Tablet:

• Long-term prevention of stable angina pectoris

• Management of chronic ischemic heart disease

• Adjunct therapy in patients with heart failure (in some cases, as prescribed by doctors)

Benefits:

• Prevents chest pain and discomfort associated with angina

• Improves exercise tolerance and physical capacity in heart patients

• Reduces the risk of angina-related complications

• Helps in long-term management of coronary artery disease

Dosage & Administration:

• Typical dosage: 20mg two or three times daily, as prescribed by the physician

• To be taken with water, preferably at the same time every day

• Should not be used for immediate relief of angina (sublingual nitroglycerin is preferred for acute attacks)

• Dosage must be adjusted depending on patient response and tolerance

Possible Side Effects:

• Headache (common, due to vasodilation)

• Dizziness or lightheadedness

• Low blood pressure (hypotension)

• Flushing or warmth in the face

• Fatigue or weakness

Precautions:

• Should be used cautiously in patients with severe low blood pressure, anemia, glaucoma, or head injury

• Not recommended for acute angina attacks

• Should not be taken together with phosphodiesterase-5 inhibitors (like sildenafil, tadalafil, vardenafil) as it may cause a dangerous drop in blood pressure

• Alcohol may intensify dizziness and low blood pressure effects

• Regular monitoring of blood pressure and heart function is advisable

Conclusion:
Isomin 20 Tablet, containing Isosorbide Mononitrate 20mg by Cipla Ltd, is a reliable and effective long-term therapy for preventing angina pectoris. By dilating blood vessels and reducing the workload on the heart, it ensures improved blood flow and oxygen delivery, helping patients maintain a better quality of life while living with coronary artery disease.