Mazetol 400 Tablet

Description

Mazetol 400 Tablet is a prescription medication containing Carbamazepine 400 mg, a highly effective anticonvulsant and mood-stabilizing agent. Manufactured by Abbott, Mazetol 400 Tablet is intended for patients requiring higher doses of Carbamazepine to manage severe epilepsy, neuropathic pain, or mood disorders such as bipolar disorder. The medication is formulated to provide consistent and reliable therapeutic effects while maintaining a favorable safety profile under medical supervision.

Carbamazepine, the active ingredient, belongs to the dibenzazepine class of anticonvulsants. It acts by stabilizing hyperactive nerve impulses in the central nervous system through inhibition of voltage-gated sodium channels. By reducing abnormal electrical activity in the brain, Carbamazepine prevents seizures, alleviates nerve pain, and supports mood stabilization in psychiatric disorders.

Therapeutic Uses:

1. Epilepsy Management: Mazetol 400 Tablet is used for controlling various types of seizures, including:

   • Generalized tonic-clonic seizures

   • Complex partial seizures

   • Mixed seizure types

   It is particularly suitable for patients who require higher doses due to the severity or frequency of their seizures. By maintaining stable neuronal activity, it helps prevent seizure recurrence and reduces the risk of complications associated with epilepsy.

2. Neuropathic Pain: Mazetol 400 Tablet is highly effective in managing trigeminal neuralgia, a condition characterized by sudden, severe, stabbing facial pain. High-dose Carbamazepine therapy can significantly reduce the intensity and frequency of these painful episodes, improving quality of life.

3. Mood Stabilization: In psychiatric practice, Mazetol 400 Tablet is prescribed as a mood stabilizer for patients with bipolar disorder, helping to control manic episodes and prevent relapse. Its effects on neurotransmitter regulation help stabilize emotional and behavioral patterns over long-term use.

Mechanism of Action:
Carbamazepine blocks sodium ion channels in hyperactive neurons, preventing repetitive firing and abnormal electrical discharges. This mechanism not only controls seizures and alleviates nerve pain but also regulates neurotransmitter activity in the brain, which is crucial for mood stabilization.

Dosage & Administration:
Mazetol 400 Tablet should be taken exactly as prescribed by a healthcare professional. The high-dose formulation is typically reserved for patients who require more potent therapy. Tablets are taken orally, preferably with food or a full glass of water, to reduce gastrointestinal irritation. Blood levels, liver function, and kidney function may need to be monitored regularly during long-term therapy. Abrupt discontinuation is not recommended, as it may precipitate seizures or mood instability.

Safety Information & Precautions:
Mazetol 400 Tablet should be used strictly under medical supervision. Patients should inform their doctor if they have:

• Allergies to anticonvulsants

• Liver or kidney disease

• Blood disorders

• Heart conditions

• History of severe dermatological reactions

Common side effects may include dizziness, drowsiness, nausea, vomiting, blurred vision, and unsteady gait. Severe adverse effects, though rare, include:

• Severe allergic reactions or rashes (including Stevens-Johnson syndrome)

• Low blood counts or anemia

• Liver toxicity or jaundice

• Psychiatric symptoms such as confusion or depression

Patients are advised to avoid alcohol and activities requiring full alertness, such as driving or operating heavy machinery, until they know how Mazetol 400 Tablet affects them.

Packaging:
Mazetol 400 Tablet is usually available in strips of 10 or 15 tablets, with each tablet containing 400 mg of Carbamazepine. This higher-dose formulation provides a convenient option for patients requiring significant therapeutic dosing, reducing the need for multiple lower-dose tablets.

Key Benefits:

• Highly effective in controlling severe or frequent seizures

• Provides substantial relief from neuropathic pain, particularly trigeminal neuralgia

• Supports long-term mood stabilization in bipolar disorder

• Manufactured by Abbott, ensuring consistent quality, purity, and safety

• Convenient high-dose formulation reduces pill burden for patients requiring larger doses

Conclusion:
Mazetol 400 Tablet is a reliable and potent treatment option for patients with severe epilepsy, neuropathic pain, and bipolar disorder. Its well-established efficacy, trusted mechanism of action, and quality manufacturing make it an essential medication for long-term management of neurological and psychiatric conditions. Proper adherence to prescribed doses and regular medical supervision ensures maximum benefit while minimizing potential risks and side effects.