Description
Brufen 400 Tablet is a non-steroidal anti-inflammatory drug (NSAID) containing Ibuprofen 400mg. It is stronger than Brufen 200 and is prescribed for moderate to severe pain, fever, and inflammation. It is commonly used in conditions like arthritis, back pain, muscle sprains, dental pain, headache, and menstrual cramps.
By reducing pain, swelling, and fever, Brufen 400 helps improve comfort and mobility in patients with painful musculoskeletal and inflammatory conditions.
Uses
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Relief of moderate pain (toothache, backache, headache, muscle pain, post-surgery pain)
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Management of fever
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Reduction of inflammation in arthritis, sprains, and soft tissue injuries
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Relief from menstrual pain (dysmenorrhea)
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Supportive treatment in musculoskeletal disorders
How it Works
Ibuprofen blocks the action of cyclooxygenase (COX-1 and COX-2) enzymes, reducing the production of prostaglandins—chemicals that cause pain, swelling, and fever. This leads to effective pain relief and reduced inflammation.
Dosage & Administration
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To be taken with or after meals to minimize stomach irritation.
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Swallow with water; do not crush or chew.
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Usual adult dose: one tablet every 6–8 hours, as prescribed.
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Do not exceed the maximum recommended daily dose.
Side Effects
Common:
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Stomach pain, indigestion, heartburn
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Nausea, vomiting
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Dizziness, drowsiness
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Headache
Serious (rare, seek medical attention):
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Stomach or intestinal bleeding/ulcer
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Severe allergic reactions (swelling, rash, breathing difficulty)
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Kidney dysfunction (low urine output, swelling of feet/ankles)
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High blood pressure or fluid retention
Precautions
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Not suitable for people with a history of stomach ulcers, gastrointestinal bleeding, severe liver/kidney disease, or heart problems.
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Caution in asthma patients.
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Avoid alcohol, as it increases the risk of stomach bleeding.
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Not recommended during pregnancy (3rd trimester) unless specifically prescribed.
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Long-term or high-dose use should be under medical supervision.
Storage
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Store in a cool, dry place away from direct sunlight.
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Keep out of reach of children.
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