Description
CIPDAPLA-M 10/1000 Tablet is a combination anti-diabetic medicine used in the management of Type 2 Diabetes Mellitus. It combines the actions of two well-established molecules:
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Dapagliflozin (10mg): A sodium-glucose co-transporter 2 (SGLT2) inhibitor. It lowers blood sugar by promoting the removal of excess glucose through urine, acting independently of insulin.
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Metformin Hydrochloride (1000mg): A biguanide. It reduces liver glucose production, improves insulin sensitivity, and decreases the absorption of glucose from the intestines.
Mechanism of Action
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Together, these ingredients decrease blood sugar more effectively than metformin alone. Dapagliflozin increases glucose excretion, while metformin reduces the amount of new glucose produced and improves the body’s response to its own insulin.
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The combination can also help reduce the risk of cardiovascular events (such as heart attacks and heart failure) in patients with diabetes and high cardiovascular risk.
Indications
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Type 2 Diabetes Mellitus: Particularly when monotherapy (single-agent treatment) does not suffice in achieving glycemic control.
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Prevention of long-term diabetes complications: Such as kidney damage, vision loss, nerve issues, and cardiovascular disease.
Benefits
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Superior glycemic control compared to metformin alone.
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May help reduce body weight and blood pressure.
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Supports heart and renal health in high-risk diabetic patients.
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Lower risk of hypoglycemia compared to some anti-diabetics.
Dosage & Administration
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Usual dose: 1 tablet once daily with food, preferably at the same time each day.
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Take whole with water; do not chew or break.
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Dose adjustments may be necessary based on kidney function, blood sugar response, and other health parameters—follow your doctor’s instructions strictly.
Common Side Effects
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Sore throat, nasal congestion, runny nose
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Nausea, vomiting, diarrhea
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Genital fungal infections, urinary tract infections
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Polyuria (frequent urination), dehydration
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Taste change, flatulence, skin rash
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Hypoglycemia (especially with missed meals, heavy exercise, or other anti-diabetic medicines)
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Dizziness, back pain
Most side effects improve as the body adapts. Notify your doctor if they persist or worsen.
Safety Advice
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Not recommended for people with type 1 diabetes or diabetic ketoacidosis.
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Caution in those with kidney or liver disorders.
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Avoid excessive alcohol intake, which may worsen risk of hypoglycemia or lactic acidosis.
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Pregnant or breastfeeding women should consult their doctor before using this medicine.
Laboratory Monitoring
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Fasting and postprandial blood glucose levels
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HbA1c (glycated hemoglobin)
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Renal function parameters
Composition Table
| Brand Name | Company | Composition | Main Indication |
|---|---|---|---|
| CIPDAPLA-M 10/1000 | Cipla Ltd | Dapagliflozin Propanediol Monohydrate 10mg + Metformin Hydrochloride IP 1000mg | Type 2 Diabetes Mellitus |
All details are verified from the manufacturer and trusted medicine databases for accuracy.
Note: Use CIPDAPLA-M 10/1000 Tablet strictly under physician supervision as part of a complete diabetes management plan, including diet, exercise, and regular monitoring.







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