COSART-H

Description

Cosart-H Tablet is a fixed-dose combination antihypertensive medicine manufactured by Cipla Ltd. It combines Losartan (50mg), an angiotensin II receptor blocker (ARB), with Hydrochlorothiazide (12.5mg), a thiazide diuretic (water pill). This combination is widely prescribed for patients with hypertension (high blood pressure) who are not adequately controlled with Losartan alone.

How It Works:

• Losartan blocks the effects of angiotensin II, a substance that causes blood vessels to constrict, thereby relaxing blood vessels and lowering blood pressure.

• Hydrochlorothiazide increases urine output by removing excess salt and water from the body, which helps reduce blood pressure and decreases strain on the heart.

Together, they provide a dual mechanism to lower blood pressure effectively and reduce the risk of serious cardiovascular complications.

Uses of Cosart-H:

• Management of essential hypertension

• Reduces the risk of stroke, heart attack, and heart failure

• Provides added benefit in patients with fluid retention (edema) due to hypertension

• Helps protect kidney function in hypertensive patients, especially those with diabetes

Key Benefits:

• Dual action therapy for better control of blood pressure

• Reduces cardiovascular risk factors

• Helps reduce swelling and water retention in hypertensive patients

• Effective in patients who do not respond to monotherapy

Dosage & Administration:

• Typically prescribed as one tablet daily, with or without food

• Should be taken at the same time each day

• Do not stop medication suddenly, as it may cause rebound hypertension

• Dose adjustments may be required in patients with kidney or liver issues

Possible Side Effects:

• Dizziness, headache, or lightheadedness

• Increased urination (due to diuretic action)

• Fatigue, weakness, or electrolyte imbalance (low potassium/sodium)

• Rare: Muscle cramps, dehydration, kidney function changes, or allergic reactions

Precautions:

• Not safe for use during pregnancy and breastfeeding

• Use with caution in patients with kidney or liver problems

• Avoid excess salt substitutes or potassium supplements unless prescribed

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended

• Avoid alcohol, as it may worsen dizziness

Conclusion:
Cosart-H Tablet, a combination of Losartan 50mg and Hydrochlorothiazide 12.5mg, manufactured by Cipla Ltd, is a highly effective treatment for hypertension. By combining an ARB with a diuretic, it ensures comprehensive blood pressure control, reduces cardiovascular risks, and provides added benefits in patients with fluid retention.