Description
Damita M 10/500 Tablet ER combines Dapagliflozin (an SGLT2 inhibitor) with Metformin (a biguanide). This fixed-dose combination is prescribed for type 2 diabetes mellitus when diet, exercise, and monotherapy are insufficient. Dapagliflozin lowers blood sugar by increasing urinary glucose excretion, while Metformin decreases glucose production in the liver and enhances insulin sensitivity. The extended-release (ER) form ensures better gastrointestinal tolerance and allows once-daily dosing.
Uses / Indications:
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Management of type 2 diabetes mellitus
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Reduces risk of long-term diabetes complications such as neuropathy, nephropathy, retinopathy, heart attack, and stroke
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Provides additional benefits for heart failure and kidney function in suitable patients
Benefits:
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Two complementary mechanisms for more effective blood sugar control
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Extended-release formulation minimizes gastric irritation from metformin
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May support weight loss and blood pressure reduction
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Lower metformin dose (500mg) suitable for initiating therapy or patients with intolerance to higher doses
How to Use:
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Take once daily with food (preferably evening meal) to reduce stomach upset.
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Swallow whole with water; do not chew or crush.
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Do not skip doses; complete therapy as prescribed.
Precautions:
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Not for type 1 diabetes or diabetic ketoacidosis (DKA).
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Caution in patients with kidney or liver impairment. Dose adjustment or monitoring may be required.
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May increase risk of urinary tract infections and genital fungal infections due to dapagliflozin.
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Metformin may very rarely cause lactic acidosis; report symptoms like extreme tiredness, shortness of breath, or abdominal pain immediately.
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Avoid excessive alcohol use.
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Pregnant or breastfeeding women should consult their doctor before use.
Possible Side Effects:
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Common: stomach upset, nausea, diarrhea, headache, increased urination
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Moderate: dehydration, dizziness, low blood pressure, genital infections
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Rare: lactic acidosis (serious), severe urinary tract infection, allergic reaction
Storage:
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Store in a cool, dry place, away from direct heat and sunlight
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