Description
Dapavel-M 10/500 Tablet ER is an extended-release oral anti-diabetic combination medicine used to manage Type 2 Diabetes Mellitus in adults. It combines Dapagliflozin (10mg) and Metformin (500mg) to provide a dual mechanism of blood glucose control.
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Dapagliflozin is an SGLT2 inhibitor that blocks glucose reabsorption in the kidneys, promoting glucose excretion via urine, helping to lower blood sugar levels.
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Metformin, a biguanide, reduces hepatic glucose production and enhances insulin sensitivity in the body.
The extended-release formulation allows for once-daily dosing, maintaining more consistent blood sugar control over 24 hours. This combination is effective in controlling both fasting and postprandial glucose levels, supporting weight management, and reducing cardiovascular risks associated with diabetes.
Uses:
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Treatment and management of Type 2 Diabetes Mellitus
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Helps achieve and maintain optimal glycemic control
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Reduces risk of heart failure and cardiovascular complications
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Supports weight reduction and better metabolic control
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Improves insulin sensitivity and glucose utilization
Dosage:
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Take the tablet once daily as prescribed by your doctor, preferably with a meal to minimize gastrointestinal side effects.
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Swallow the tablet whole with water; do not crush, chew, or break it.
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If a dose is missed, take it as soon as possible unless it is nearly time for your next dose. Do not double doses.
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Dose adjustments may be needed based on blood sugar levels and treatment response.
How to Use:
Take Dapavel-M 10/500 Tablet ER at the same time each day for consistent blood glucose control. Combine with a balanced diet, regular exercise, and routine blood sugar monitoring. Continue therapy even if blood sugar appears normal unless advised by your doctor.
Precautions:
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Not intended for Type 1 Diabetes or diabetic ketoacidosis.
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Avoid alcohol, as it increases risk of hypoglycemia and lactic acidosis.
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Use cautiously in patients with kidney, liver, or heart issues.
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Maintain adequate hydration to prevent dehydration and urinary tract infections.
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Regularly monitor renal function and blood glucose levels.
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Consult your doctor before use during pregnancy or breastfeeding.
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Be cautious when combined with diuretics or blood pressure medicines.
Side Effects:
Common:
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Frequent urination
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Urinary tract infection (UTI)
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Nausea, vomiting, or stomach discomfort
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Increased thirst
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Low blood sugar (when combined with other anti-diabetic drugs)
Less Common:
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Fatigue or dizziness
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Back pain
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Constipation or mild loss of appetite
Serious (seek immediate medical attention):
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Signs of lactic acidosis (muscle pain, tiredness, rapid breathing)
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Ketoacidosis (abdominal pain, vomiting, confusion)
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Severe urinary or genital infections
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Allergic reactions (rash, swelling, difficulty breathing)







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