Description
Dapavel Trio 500 Tablet ER is a triple-combination anti-diabetic medication designed for adults with Type 2 Diabetes Mellitus. It combines Dapagliflozin (10mg), Metformin (500mg), and Sitagliptin (100mg) in an extended-release formulation, allowing for once-daily dosing and steady blood sugar control throughout the day.
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Dapagliflozin, an SGLT2 inhibitor, lowers blood sugar by preventing glucose reabsorption in the kidneys, increasing glucose excretion via urine.
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Metformin, a biguanide, reduces hepatic glucose production and enhances insulin sensitivity, improving glucose utilization.
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Sitagliptin, a DPP-4 inhibitor, enhances incretin hormones, which increase insulin release post-meal and decrease glucose production by the liver.
This combination effectively targets fasting and postprandial blood glucose levels, supports weight management, and reduces the risk of cardiovascular complications associated with diabetes.
Uses:
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Management of Type 2 Diabetes Mellitus
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Helps maintain steady blood glucose levels
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Reduces risk of diabetes-related cardiovascular complications
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Supports weight management
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Improves insulin secretion and glucose utilization
Dosage:
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Take the tablet exactly as prescribed by your doctor, usually once daily, with or after a meal.
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Swallow the tablet whole with water; do not crush or chew.
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If a dose is missed, take it as soon as possible unless it is near the next dose. Do not double doses.
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Dosage adjustments may be made based on blood glucose levels and individual response.
How to Use:
Take Dapavel Trio 500 Tablet ER at the same time each day for consistent blood sugar control. Follow a healthy diet, engage in regular exercise, and monitor blood glucose levels regularly. Continue therapy even if your blood sugar appears normal unless directed otherwise by your healthcare provider.
Precautions:
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Not suitable for Type 1 Diabetes or diabetic ketoacidosis.
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Avoid alcohol, as it may increase the risk of hypoglycemia and lactic acidosis.
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Use caution in patients with kidney, liver, or heart disease.
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Maintain adequate hydration to prevent urinary tract infections and dehydration.
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Monitor kidney function and blood sugar levels regularly.
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Consult a doctor before use during pregnancy or breastfeeding.
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Be cautious if using diuretics or blood pressure medications.
Side Effects:
Common:
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Frequent urination
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Urinary tract infections
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Nausea, stomach upset, or diarrhea
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Low blood sugar (hypoglycemia) when combined with other diabetes medications
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Mild dehydration
Less Common:
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Dizziness or fatigue
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Back pain
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Constipation
Serious (seek medical attention):
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Severe hypoglycemia (sweating, trembling, confusion, fainting)
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Lactic acidosis (muscle pain, fatigue, difficulty breathing)
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Ketoacidosis (abdominal pain, nausea, vomiting)
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Severe urinary or genital infections
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Allergic reactions (rash, swelling, difficulty breathing)
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