Description
ESGIPYRIN DS Injection is a non-steroidal anti-inflammatory drug (NSAID) that contains Diclofenac (25mg/ml) as its active ingredient. It is widely used for the management of pain, inflammation, and swelling associated with various medical conditions. The injection form allows for fast relief in acute cases where oral medicines may not be suitable or effective.
Diclofenac works by reducing the production of chemical messengers called prostaglandins, which are responsible for causing pain, fever, and inflammation. ESGIPYRIN DS Injection is usually administered in a clinical or hospital setting under the supervision of a healthcare professional.
Uses of ESGIPYRIN DS Injection
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Relief from moderate to severe pain (post-surgical, injury-related, or musculoskeletal pain)
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Treatment of inflammation and swelling in conditions such as arthritis, spondylitis, and sports injuries
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Management of acute musculoskeletal disorders
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Pain associated with renal colic or gallstones
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Short-term treatment of post-operative pain when oral therapy is not possible
How it Works
Diclofenac in ESGIPYRIN DS Injection inhibits the enzyme cyclooxygenase (COX), which is responsible for the formation of prostaglandins. By lowering prostaglandin levels, the medicine reduces pain, swelling, stiffness, and fever, providing quick symptomatic relief.
Dosage & Administration
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The injection is usually given intramuscularly (IM) by a doctor or nurse.
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The exact dosage depends on the patient’s age, weight, and severity of the condition.
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It is meant for short-term use only; prolonged use may increase the risk of side effects.
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Not for self-administration – should always be given under medical supervision.
Possible Side Effects
Common side effects:
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Pain, redness, or swelling at the injection site
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Nausea, vomiting, or indigestion
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Headache or dizziness
Serious side effects (seek immediate medical attention):
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Stomach ulcers, bleeding, or severe abdominal pain
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Allergic reactions such as rash, itching, swelling of face/lips
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Breathing difficulties, chest pain (rare but serious cardiovascular risks)
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Liver or kidney dysfunction symptoms (yellowing of eyes/skin, dark urine)
Warnings & Precautions
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Pregnancy & Breastfeeding: Not recommended, especially in the third trimester of pregnancy.
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Heart & Kidney Patients: Use with caution in people with heart disease, high blood pressure, or kidney impairment.
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Stomach Issues: May increase the risk of ulcers and gastrointestinal bleeding – inform your doctor if you have a history of stomach problems.
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Drug Interactions: Can interact with blood thinners, other NSAIDs, steroids, and certain antihypertensive medicines.
Storage Instructions
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Store in a cool, dry place, away from direct light.
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Keep out of reach of children.
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Do not freeze.
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