Description
Etocox 120 mg Tablet contains Etoricoxib, a selective COX-2 inhibitor (non-steroidal anti-inflammatory drug – NSAID) that provides effective relief from pain, inflammation, and swelling. Unlike traditional NSAIDs, it selectively inhibits the COX-2 enzyme, reducing pain and inflammation with a lower risk of stomach ulcers compared to non-selective NSAIDs.
It is commonly prescribed for conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and acute pain (like dental or post-surgical pain). Due to its strong analgesic and anti-inflammatory action, it is usually recommended for short-term or as-needed use under medical supervision.
Uses / Indications
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Osteoarthritis and rheumatoid arthritis (joint pain, stiffness, inflammation)
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Ankylosing spondylitis (chronic spinal arthritis)
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Acute gouty arthritis (pain and swelling in joints due to uric acid crystals)
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Acute pain management (dental pain, post-operative pain, musculoskeletal pain)
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Primary dysmenorrhea (menstrual pain)
How It Works (Mechanism of Action)
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Etoricoxib (120 mg): Selectively inhibits the COX-2 enzyme, which is responsible for prostaglandin production during inflammation.
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Reduced prostaglandin levels → decreased pain, swelling, and stiffness.
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Selectivity for COX-2 helps reduce gastrointestinal side effects compared to traditional NSAIDs like diclofenac or ibuprofen.
Dosage & Administration
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Typical adult dose: 60–120 mg once daily, depending on condition severity.
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For acute pain or gout, 120 mg once daily is often prescribed for a short duration (usually not more than 8 days).
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Should be taken with or without food, but taking with food may reduce stomach upset.
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Always follow the doctor’s instructions; do not exceed prescribed dose.
Side Effects
Common:
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Stomach pain, indigestion, heartburn
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Headache, dizziness
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Swelling of hands, ankles, or feet (fluid retention)
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High blood pressure
Serious (rare):
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Increased risk of heart attack, stroke, or blood clotting (especially with long-term/high-dose use)
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Stomach ulcers, gastrointestinal bleeding (though less common than with traditional NSAIDs)
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Severe allergic reactions (rash, itching, swelling, breathing difficulty)
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Liver or kidney dysfunction (yellowing of eyes/skin, dark urine, fatigue)
Precautions & Warnings
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Not suitable for patients with severe heart disease, stroke history, uncontrolled high blood pressure, severe liver/kidney disease.
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Should be used cautiously in elderly patients and those with cardiovascular risk factors.
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Not recommended during pregnancy, especially in the third trimester, or while breastfeeding.
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Alcohol should be avoided, as it may increase the risk of stomach irritation and liver issues.
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Use the lowest effective dose for the shortest duration to minimize side effects.
Summary
Etocox 120 mg Tablet (Etoricoxib 120 mg) is a selective COX-2 inhibitor used for the treatment of arthritis, gout, and acute pain conditions. It provides powerful pain and inflammation relief while reducing the risk of stomach-related side effects compared to traditional NSAIDs. However, it carries a higher risk of cardiovascular complications, so it should be used cautiously and only under medical supervision.
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