Flexon MR Tablet

Description

Flexon MR Tablet is a muscle relaxant and pain reliever combination that helps in managing musculoskeletal pain, spasms, and inflammation. It combines three active ingredients:

• Ibuprofen – a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and swelling.

• Paracetamol – an analgesic and antipyretic that provides additional pain relief and reduces fever.

• Chlorzoxazone – a centrally acting muscle relaxant that relieves muscle stiffness and spasms.

Together, these agents provide comprehensive relief in conditions like back pain, neck pain, sprains, strains, and arthritis-associated muscle stiffness.

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Uses / Indications

• Muscle pain and stiffness

• Pain due to sprains, strains, and injuries

• Back pain, neck pain, and shoulder stiffness

• Arthritis and spondylitis with associated muscle spasms

• Post-surgical or post-traumatic musculoskeletal pain

• Headache or tension-type headache with muscular tension

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How It Works (Mechanism of Action)

• Ibuprofen (400 mg): Inhibits COX enzymes → decreases prostaglandin formation → reduces inflammation, pain, and swelling.

• Paracetamol (325 mg): Acts on the brain’s thermoregulatory and pain-control centers → reduces fever and enhances pain relief.

• Chlorzoxazone (250 mg): Acts on the spinal cord and brain centers to relieve muscle spasms and stiffness, improving mobility.

This triple combination ensures pain relief + anti-inflammatory effect + muscle relaxation.

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Dosage & Administration

• Typical adult dose: One tablet 2–3 times a day, as prescribed.

• Should be taken with food or milk to minimize stomach irritation.

• Do not exceed the recommended dose to avoid liver or kidney toxicity.

• Duration of use should be short-term, unless advised by a doctor.

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Side Effects

Common:

• Nausea, vomiting, stomach pain

• Heartburn, indigestion

• Drowsiness, dizziness

• Tiredness or weakness

Serious (rare):

• Liver damage (due to paracetamol overdose)

• Stomach bleeding or ulcers (with prolonged ibuprofen use)

• Allergic reactions (rash, swelling, breathing difficulty)

• Kidney dysfunction

• Severe drowsiness or loss of coordination (from chlorzoxazone)

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Precautions & Warnings

• Not recommended for patients with liver disease, kidney disease, stomach ulcers, asthma triggered by NSAIDs, or history of gastrointestinal bleeding.

• Avoid alcohol, as it increases the risk of liver damage and stomach irritation.

• Should not be used with other medicines containing paracetamol, ibuprofen, or muscle relaxants.

• May cause drowsiness or dizziness → avoid driving or operating machinery until response is known.

• Use cautiously in elderly patients and those with hypertension or heart disease.

• Not safe in pregnancy (especially last trimester) or during breastfeeding without medical advice.

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Summary

Flexon MR Tablet (Ibuprofen 400 mg + Paracetamol 325 mg + Chlorzoxazone 250 mg) is a muscle relaxant and pain reliever used for musculoskeletal pain, stiffness, and spasms. It provides comprehensive relief by reducing inflammation, controlling pain, and relaxing tight muscles. While effective, it should be used at the lowest effective dose for the shortest possible duration to avoid risks such as liver stress, kidney damage, stomach ulcers, or excessive drowsiness.