Fosfocin Powder

Description

Fosfocin Powder contains Fosfomycin, a broad-spectrum antibiotic primarily used to treat urinary tract infections (UTIs) caused by susceptible bacteria. It comes as a single-dose sachet (3 g), usually dissolved in water and taken orally.

Fosfomycin is especially valuable in uncomplicated UTIs in women, including infections caused by resistant organisms such as E. coli. Its single-dose regimen ensures patient compliance, making it an effective and convenient therapy.

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Uses / Indications

• Acute uncomplicated urinary tract infections (cystitis) in women

• Infections caused by multidrug-resistant bacteria (e.g., ESBL-producing E. coli)

• Sometimes used in combination therapy for complicated or recurrent UTIs

• May be used off-label for certain bacterial infections as guided by a doctor

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How It Works (Mechanism of Action)

• Fosfomycin (3 g): A bactericidal antibiotic.

• Inhibits enolpyruvyl transferase enzyme, which is essential for bacterial cell wall synthesis.

• Prevents bacteria from forming their protective wall → leads to bacterial death.

• Works against both gram-positive and gram-negative bacteria, including resistant strains.

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Dosage & Administration

• Adults (female patients): One sachet (3 g) as a single oral dose.

• Should be dissolved in a glass of water and taken on an empty stomach, preferably before bedtime after urination.

• Not usually recommended for men, children, or complicated infections unless prescribed by a doctor.

• Always follow the doctor’s advice for special conditions (e.g., pregnancy, resistant infections).

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Side Effects

Common:

• Diarrhea, nausea, stomach upset

• Headache, dizziness

• Vaginitis (in some women)

Serious (rare):

• Severe allergic reaction (rash, swelling, breathing difficulty)

• Persistent diarrhea due to Clostridium difficile infection

• Liver problems (elevated liver enzymes, jaundice)

• Low potassium levels (rare electrolyte imbalance)

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Precautions & Warnings

• Contraindicated in patients with known allergy to Fosfomycin.

• Use with caution in kidney disease patients; dose adjustment may be needed.

• May interact with drugs that increase gastrointestinal motility (e.g., metoclopramide), which can reduce absorption.

• Not effective against pyelonephritis (kidney infections) or complicated UTIs unless specifically advised by a doctor.

• Safe in pregnancy and breastfeeding only under medical supervision.

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Summary

Fosfocin Powder (Fosfomycin 3 g) is a single-dose oral antibiotic for the treatment of acute uncomplicated urinary tract infections in women. Its ease of administration, broad antibacterial coverage, and effectiveness against resistant bacteria make it a preferred choice. However, it should be used cautiously and only under prescription to avoid misuse and antibiotic resistance.