Gabamax NT 50/10 Tablet

Description

Gabamax NT 50/10 Tablet is a combination medicine used for the treatment of neuropathic pain (nerve-related pain). It combines Pregabalin, an anticonvulsant with analgesic properties, and Nortriptyline, a tricyclic antidepressant with pain-modulating effects.

This dual-action approach helps in reducing nerve pain, improving sleep, and enhancing quality of life in patients suffering from chronic pain conditions such as diabetic neuropathy, sciatica, postherpetic neuralgia, and fibromyalgia.

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Uses / Indications

• Neuropathic pain due to diabetes, shingles, injury, or spinal conditions

• Postherpetic neuralgia (persistent pain after shingles)

• Peripheral neuropathy

• Fibromyalgia (generalized body pain with fatigue and sleep problems)

• Chronic nerve-related pain not relieved by conventional painkillers

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How It Works (Mechanism of Action)

• Pregabalin (50 mg):

  • Binds to calcium channels in nerve cells.

  • Reduces the release of pain-signaling chemicals (neurotransmitters).

  • Provides analgesic, anticonvulsant, and anxiolytic benefits.

• Nortriptyline (10 mg):

  • A tricyclic antidepressant (TCA).

  • Increases brain levels of serotonin and norepinephrine, which modulate pain perception.

  • Also helps in improving mood and sleep quality.

Together, they provide synergistic relief from nerve pain while improving emotional well-being and sleep.

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Dosage & Administration

• Typical dose: One tablet once or twice daily, as prescribed.

• Should be taken with or without food, at the same time each day.

• Dose adjustments may be required in elderly patients or those with kidney/liver problems.

• Do not stop suddenly without medical guidance → may cause withdrawal symptoms.

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Side Effects

Common:

• Drowsiness, dizziness, sleepiness

• Blurred vision, dry mouth

• Constipation, weight gain

• Swelling in hands/feet

• Difficulty in concentration

Serious (rare):

• Allergic reactions (rash, swelling, breathing difficulty)

• Mood changes, depression, suicidal thoughts

• Irregular heartbeat, chest pain

• Severe constipation or urinary retention

• Low blood pressure or fainting

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Precautions & Warnings

• May cause sedation → avoid driving or operating machinery.

• Should be used cautiously in patients with heart disease, kidney/liver problems, glaucoma, or psychiatric conditions.

• Alcohol should be avoided as it can increase drowsiness and dizziness.

• Risk of suicidal thoughts or behavior → close monitoring needed.

• Safe use during pregnancy and breastfeeding should be under medical advice only.

• Not recommended for children unless specifically prescribed.

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Summary

Gabamax NT 50/10 Tablet (Pregabalin 50 mg + Nortriptyline 10 mg) is a nerve pain management therapy that works by calming overactive nerves and enhancing pain tolerance. It is highly beneficial for neuropathic pain, fibromyalgia, and postherpetic neuralgia, improving both physical and psychological well-being. However, it should be used strictly under medical supervision due to its potential side effects such as drowsiness, mood changes, and cardiac effects.