Gabaneuron NT 400 Tablet

Description

Gabaneuron NT 400 Tablet is a combination medicine prescribed for the management of neuropathic pain (nerve pain) caused by diabetes, shingles, spinal cord injuries, or other chronic nerve damage conditions. It contains Gabapentin, an anticonvulsant with pain-relieving effects, and Nortriptyline, a tricyclic antidepressant (TCA) that reduces pain perception and improves mood.

The higher Gabapentin dose (400 mg) in this formulation makes it suitable for patients with moderate to severe nerve pain or those who do not respond adequately to lower strengths.

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Uses / Indications

• Neuropathic pain (diabetic neuropathy, postherpetic neuralgia, sciatica)

• Peripheral neuropathy

• Fibromyalgia (chronic muscle pain with fatigue and poor sleep)

• Chronic pain syndromes unresponsive to regular analgesics

• Adjunct treatment in seizure disorders (in some cases)

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How It Works (Mechanism of Action)

• Gabapentin (400 mg):

  • Acts on voltage-gated calcium channels in the brain and spinal cord.

  • Reduces overactive nerve signaling that causes persistent pain.

  • Provides both anticonvulsant and analgesic effects.

• Nortriptyline (10 mg):

  • A tricyclic antidepressant that enhances serotonin and norepinephrine levels.

  • Helps reduce the intensity of pain signals and improves mood, sleep, and emotional well-being.

Together, they provide effective relief from nerve pain, improve quality of life, and support long-term nerve health.

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Dosage & Administration

• Usual dose: One tablet daily, or as prescribed by the doctor.

• Can be taken with or without food.

• Dose may be increased gradually depending on patient tolerance and response.

• Should be taken at the same time every day for best results.

• Do not discontinue suddenly; tapering is required to prevent withdrawal effects.

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Side Effects

Common:

• Drowsiness, dizziness, sleepiness

• Dry mouth, constipation

• Weight gain, swelling in feet/ankles

• Blurred vision, tiredness

Serious but rare:

• Mood swings, depression, suicidal thoughts

• Palpitations, irregular heartbeat

• Confusion, memory problems (especially in elderly)

• Severe allergic reactions (rash, swelling, difficulty breathing)

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Precautions & Warnings

• Causes sedation → avoid driving, heavy machinery, or activities requiring alertness.

• Avoid alcohol as it increases drowsiness and other side effects.

• Use with caution in patients with heart disease, kidney problems, glaucoma, or psychiatric conditions.

• Pregnant or breastfeeding women should take only under strict medical advice.

• Elderly patients may be more sensitive to side effects such as dizziness, confusion, or balance problems.

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Summary

Gabaneuron NT 400 Tablet (Gabapentin 400 mg + Nortriptyline 10 mg) is a potent medicine for moderate to severe neuropathic pain. It not only reduces nerve pain but also improves mood, sleep, and overall quality of life. The higher dose of Gabapentin makes it suitable for patients who require stronger relief, but it must be used with medical supervision due to risks of drowsiness, mood changes, and heart-related side effects.