Grandem Syrup

Description

Grandem Syrup contains Granisetron (1mg/5ml), an antiemetic medicine that belongs to the class of 5-HT3 receptor antagonists. It is primarily prescribed to prevent and manage nausea and vomiting caused by chemotherapy, radiotherapy, or surgical procedures. The syrup form makes it particularly suitable for children and patients who cannot swallow tablets.

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Uses / Indications

• Chemotherapy-induced nausea and vomiting (CINV)

• Radiotherapy-induced nausea and vomiting

• Post-operative nausea and vomiting (PONV)

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How It Works

• Granisetron blocks serotonin (5-HT3) receptors in the brain and gastrointestinal tract.

• Serotonin is released during chemotherapy, radiation, or surgery and triggers the vomiting reflex.

• By blocking serotonin’s action, the medicine helps prevent and relieve nausea and vomiting.

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Dosage & Administration

• To be taken orally as prescribed by the doctor.

• Dose depends on age, weight, and medical condition.

• Usually given before and/or after chemotherapy/radiotherapy or surgery.

• Should be measured using the provided measuring cup/spoon for accurate dosing.

• Do not exceed the recommended dose.

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Side Effects

Common:

• Headache

• Constipation

• Diarrhea

• Drowsiness or fatigue

Less common:

• Dizziness

• Abdominal discomfort

• Sleep disturbances

Serious (rare):

• Allergic reactions (rash, itching, swelling of face/tongue, breathing difficulty)

• Irregular heartbeat (QT prolongation)

• Severe constipation or abdominal pain

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Precautions & Warnings

• Use under strict medical supervision.

• Inform doctor if patient has heart problems, electrolyte imbalance, or liver disease.

• Should not be given to patients allergic to Granisetron or other 5-HT3 antagonists (e.g., Ondansetron).

• Use in pregnancy and breastfeeding only if prescribed by a doctor.

• Not recommended for infants unless specifically directed by a pediatrician.

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Summary

Grandem Syrup (Granisetron 1mg/5ml) is an effective antiemetic solution used to manage nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery. The liquid form is especially useful for children and elderly patients who may have difficulty swallowing tablets. It is safe and effective when used under medical supervision.