Description
I-Tyza SB 100 Capsule contains Itraconazole (100mg), a triazole class antifungal medicine. It is widely prescribed to treat skin, nail, and mucosal fungal infections, as well as some systemic fungal diseases. The “SB” formulation indicates Super Bioavailability, which means this capsule is specially designed to ensure better absorption of itraconazole compared to conventional forms, even at lower doses.
By blocking ergosterol synthesis, Itraconazole damages the fungal cell membrane, ultimately leading to the death of the fungus.
Uses
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Fungal nail infections (Onychomycosis)
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Ringworm, Athlete’s foot, Jock itch
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Oral and esophageal candidiasis
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Vaginal candidiasis
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Dermatophytosis (skin fungal infections)
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Systemic fungal infections (histoplasmosis, aspergillosis, blastomycosis)
How It Works
Itraconazole inhibits the fungal enzyme lanosterol 14α-demethylase, blocking the production of ergosterol, a key component of fungal cell membranes. Without ergosterol, the fungal cells weaken, leak, and eventually die. The SB (Super Bioavailability) version ensures that the body absorbs more itraconazole from each capsule, making treatment more effective.
Benefits
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Improved absorption due to SB technology
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Effective against both superficial and systemic fungal infections
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Useful for patients with poor response to standard itraconazole capsules
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Prevents recurrence of fungal infections
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Suitable for long-term therapy under medical guidance
Directions for Use
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Take the capsule after a full meal for maximum absorption.
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Swallow whole with water; do not chew or crush.
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Dosage varies depending on the type and severity of infection.
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Complete the full prescribed course, even if symptoms improve.
Safety Information
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Common side effects: stomach upset, nausea, vomiting, diarrhea, dizziness, headache.
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May increase liver enzymes; liver function tests are advised during prolonged use.
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Avoid alcohol during treatment.
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Use with caution in patients with heart failure, liver disease, or kidney disease.
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Can interact with medicines like antacids, rifampicin, statins, warfarin, and antihistamines.
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Not recommended during pregnancy unless absolutely necessary; caution advised in breastfeeding.
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