Mega-CV 1.2gm Injection

Description

Mega-CV 1.2gm Injection is a high-strength, parenteral antibiotic designed for moderate to severe bacterial infections that require intravenous or intramuscular administration. It contains:

• Amoxycillin (1000mg): A broad-spectrum penicillin antibiotic that inhibits bacterial cell wall synthesis, leading to bacterial death.

• Clavulanic Acid (200mg): A beta-lactamase inhibitor that protects Amoxycillin from degradation by resistant bacteria, enhancing its antibacterial efficacy.

This formulation ensures rapid and effective systemic delivery of the antibiotic, particularly for infections where oral administration is not feasible.

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Uses / Indications

• Severe respiratory tract infections (pneumonia, bronchitis, sinusitis)

• Severe ENT infections (otitis media, tonsillitis, pharyngitis)

• Skin and soft tissue infections

• Urinary tract infections (UTIs)

• Bone and joint infections

• Infections requiring hospital-based therapy or rapid systemic antibiotic delivery

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How It Works

• Amoxycillin disrupts bacterial cell wall synthesis, leading to bacterial lysis and death.

• Clavulanic Acid inhibits beta-lactamase enzymes produced by resistant bacteria, protecting Amoxycillin from degradation.

• This combination provides broad-spectrum antibacterial coverage, including beta-lactamase-producing bacteria.

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Dosage & Administration

• Administered intravenously (IV) or intramuscularly (IM) as prescribed by a healthcare professional.

• Dosage frequency depends on infection severity, patient condition, and renal function.

• Usually infused over 20–30 minutes for IV administration.

• Duration of therapy depends on infection type and clinical response.

• Must be prepared and administered under medical supervision.

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Side Effects

Common:

• Mild nausea or vomiting

• Injection site pain or swelling

• Diarrhea

Less Common / Rare:

• Allergic reactions (rash, itching, swelling)

• Headache or dizziness

• Mild liver enzyme elevation

Serious (rare):

• Severe allergic reactions (anaphylaxis)

• Liver dysfunction (jaundice, elevated liver enzymes)

• Severe diarrhea due to Clostridium difficile infection

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Precautions & Warnings

• Avoid in patients with penicillin allergy.

• Use cautiously in patients with renal or liver impairment.

• Monitor patients during IV infusion for allergic reactions.

• Ensure correct dilution and administration to prevent local irritation.

• Complete the prescribed course even if symptoms improve early.

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Summary

Mega-CV 1.2gm Injection (Amoxycillin 1000mg + Clavulanic Acid 200mg) is a high-strength parenteral antibiotic for moderate to severe bacterial infections, particularly those caused by beta-lactamase-producing bacteria. It ensures rapid systemic delivery and should be administered under strict medical supervision with adherence to dosing and monitoring guidelines.