Mikacin Injection

Description

Mikacin Injection contains Amikacin, an aminoglycoside antibiotic. It is used to treat serious bacterial infections, particularly those caused by Gram-negative bacteria that are resistant to other antibiotics. It is typically administered in a hospital setting under medical supervision.

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Uses

• Severe respiratory tract infections (pneumonia, bronchitis)

• Urinary tract infections (UTIs)

• Intra-abdominal infections

• Septicemia (blood infections)

• Bone and joint infections

• Skin and soft tissue infections

• Hospital-acquired infections caused by multidrug-resistant bacteria

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How It Works

Amikacin works by binding to bacterial ribosomes (30S subunit), thereby preventing protein synthesis. This action kills the bacteria and controls the spread of infection.

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Side Effects

Common side effects:

• Pain or irritation at the injection site

• Nausea, vomiting

• Fever, headache

Serious but less common side effects:

• Nephrotoxicity (kidney damage)

• Ototoxicity (hearing loss, ringing in the ears, balance problems)

• Neuromuscular weakness (rare)

• Allergic reactions (rash, itching, swelling, breathing difficulty)

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Precautions

• Should be used with caution in patients with kidney problems and hearing disorders

• Requires monitoring of kidney function and drug blood levels during prolonged therapy

• Avoid combining with other nephrotoxic or ototoxic drugs unless prescribed

• Use in pregnancy and breastfeeding only if clearly needed and prescribed by a doctor

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Administration

• Administered intravenously (IV) or intramuscularly (IM) by a healthcare professional

• Dosage depends on infection type, severity, and patient’s kidney function