Omcef 200 Tablet

Description

Omcef 200 Tablet is a combination antibiotic containing Cefixime, a third-generation cephalosporin, and Ofloxacin, a fluoroquinolone. This combination is used to treat moderate to severe bacterial infections, particularly when infections are resistant to a single antibiotic.

The higher 200mg/200mg strength is generally prescribed for adults or older children with more severe infections.

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Uses

• Respiratory tract infections – bronchitis, pneumonia, sinusitis, tonsillitis

• Urinary tract infections (UTIs)

• Gastrointestinal infections – enteric fever, gastroenteritis

• Skin and soft tissue infections

• Ear infections (otitis media)

• Bone and joint infections

• Other bacterial infections resistant to monotherapy

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How It Works

• Cefixime (200mg): Inhibits bacterial cell wall synthesis, causing bacterial death.

• Ofloxacin (200mg): Inhibits bacterial DNA gyrase and topoisomerase IV, preventing bacterial replication.

Together, they provide broad-spectrum antibacterial activity, effective against Gram-positive and Gram-negative bacteria.

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Side Effects

Common:

• Nausea, vomiting, diarrhea

• Stomach discomfort or abdominal pain

• Headache, dizziness

• Mild skin rash

Serious (rare):

• Severe allergic reactions (swelling, difficulty breathing, anaphylaxis)

• Tendonitis or tendon rupture (linked to Ofloxacin)

• Liver enzyme abnormalities

• Blood disorders (low platelets, anemia, leukopenia)

• Clostridium difficile-associated diarrhea

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Precautions

• Avoid in patients allergic to cephalosporins or fluoroquinolones

• Dose adjustment may be needed in renal or hepatic impairment

• Not recommended in pregnancy or breastfeeding unless prescribed

• Avoid excessive sun exposure due to photosensitivity risk (from Ofloxacin)

• Use caution in elderly patients or those with pre-existing tendon or joint problems

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Administration

• Taken orally, usually twice daily or as prescribed by a doctor

• Swallow with water, do not crush or chew

• Complete the full prescribed course to prevent antibiotic resistance