Description
PTU Tablet contains Propylthiouracil (50mg), a medicine that belongs to the class of antithyroid agents. It is mainly prescribed to manage hyperthyroidism (overactive thyroid), including Graves’ disease, and to control symptoms of excessive thyroid hormone production.
Propylthiouracil works by reducing the formation of thyroid hormones (T3 and T4) in the thyroid gland and also blocks the conversion of T4 to the more active T3 in the body. This helps bring thyroid hormone levels back to normal, thereby controlling symptoms like rapid heartbeat, excessive sweating, weight loss, anxiety, and tremors.
Uses
PTU Tablet is prescribed for:
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Hyperthyroidism (overactive thyroid)
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Graves’ disease (autoimmune hyperthyroidism)
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Thyrotoxic crisis/thyroid storm (severe hyperthyroidism)
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As preparation before thyroid surgery or radioactive iodine therapy
Advantages
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Effectively controls excess thyroid hormone levels.
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Provides symptomatic relief from palpitations, tremors, heat intolerance, and nervousness.
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Useful when other treatments (like methimazole) are not tolerated.
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Can be used during thyroid storm, a life-threatening condition.
Possible Side Effects
Common side effects may include:
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Nausea, vomiting, stomach upset
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Rash, itching, or mild skin reactions
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Headache, dizziness, joint or muscle pain
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Hair thinning
👉 Rare but serious side effects:
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Liver problems (jaundice, dark urine, abdominal pain)
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Low white blood cell count (agranulocytosis) leading to infections, sore throat, or fever
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Bleeding or easy bruising
If any severe reaction occurs, immediate medical help is required.
Precautions
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Regular monitoring of thyroid function tests and liver function tests is essential.
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Inform the doctor if you have a history of liver disease, blood disorders, or previous drug reactions.
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Should not be used during pregnancy, except when clearly prescribed (may be considered in the first trimester if needed).
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Avoid alcohol as it may increase liver risks.
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Report any sore throat, fever, or signs of infection immediately.
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Take the medicine exactly as prescribed; do not stop suddenly without medical advice.
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