Description
QUTIDEP-100 SR contains quetiapine 100 mg in a sustained release (SR) formulation—an atypical antipsychotic used for prolonged, steady effect in various psychiatric disorders. It is supplied in a blister pack for once- or twice-daily oral dosing.
Clinical Uses
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Schizophrenia: Treatment of delusions, auditory/visual hallucinations, disorganized thoughts, and social withdrawal.
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Bipolar disorder: Control of mania, hypomania, depressive episodes, and as a mood stabilizer for long-term prevention of recurrence.
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Mania: Used in acute episodes and for maintenance.
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Adjunctive therapy in major depressive disorder (in select cases).
Mechanism of Action
Quetiapine works as a dopamine and serotonin receptor antagonist, rebalancing neurotransmitters in the brain. This leads to improvements in psychosis, mood fluctuation, and behavioral disturbances.
Dosage & Administration
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Usually started at 50–100 mg daily with slow dose titration based on response and side effects.
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SR (sustained release) formulation is generally taken once daily, in the evening or as advised; swallow whole, do not crush or chew.
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Dose adjustments are made by the psychiatrist, with higher maintenance doses for severe illness (up to 800 mg/day).
Common Side Effects
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Drowsiness, dizziness, dry mouth, constipation, increased appetite, weight gain, orthostatic hypotension (drop in BP with standing), fatigue.
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Monitor for metabolic changes: increases in cholesterol, triglycerides, blood sugar.
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Rare: abnormal movements (tardive dyskinesia), severe mood changes, neuroleptic malignant syndrome.
Precautions & Safety Advice
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Use caution in elderly, diabetes, heart disease, and those with liver impairment.
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May cause sedation—avoid hazardous activity until effects are known.
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Regular follow-up for metabolic, heart, and blood profile monitoring is recommended for long-term therapy.
QUTIDEP-100 SR is a prescription sustained-release antipsychotic tablet for round-the-clock management of schizophrenia, bipolar disorder, and mania.
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