Description
Valance OD 1g Tablet PR is an antiepileptic and mood stabilizing medicine that contains Divalproex Sodium 1000mg in a prolonged-release (PR) formulation. It helps in controlling seizures, managing bipolar disorder, and preventing migraine headaches. The prolonged-release property ensures a steady and sustained release of the medicine, allowing for better control of symptoms with fewer daily doses.
Uses
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Epilepsy: Controls different types of seizures in adults and children.
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Bipolar Disorder: Stabilizes mood, reduces frequency of manic and depressive episodes.
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Migraine Prophylaxis: Helps prevent migraine attacks.
How it Works
Divalproex increases the concentration of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. This calms excessive nerve activity, prevents abnormal electrical discharges, and maintains brain stability, thereby controlling seizures, mood disturbances, and migraines.
Dosage & Administration
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To be taken only under medical supervision.
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Swallow whole with water; do not crush or chew.
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Usually taken once daily, preferably at the same time each day.
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Dosage may be adjusted based on age, weight, and medical response.
Side Effects
Common:
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Nausea, vomiting, abdominal discomfort
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Drowsiness, dizziness, tremors
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Weight gain, increased appetite
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Temporary hair loss
Serious (seek immediate medical help):
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Liver problems (yellowing of skin/eyes, dark urine, persistent nausea)
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Pancreatitis (severe stomach pain, vomiting)
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Unusual bleeding or bruising
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Severe allergic reactions (rash, swelling, difficulty breathing)
Precautions
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Not recommended in pregnancy, especially in the first trimester, due to risk of birth defects.
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Regular liver function, pancreas function, and blood tests are advised during treatment.
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Avoid alcohol and other medicines that depress the central nervous system.
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Use with caution in patients with liver disease, kidney disease, or blood clotting disorders.
Storage
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Store in a cool, dry place below 25°C.
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Protect from moisture and direct sunlight.
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Keep out of reach of children.
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