Description
Ziglim-M 2 Tablet PR is a prescription anti-diabetic medicine that combines Glimepiride, a sulfonylurea, and Metformin, a biguanide. It is prescribed for adults with Type 2 Diabetes Mellitus whose blood sugar levels are not adequately controlled with diet, exercise, or a single anti-diabetic medicine. The prolonged-release formulation provides gradual release of Metformin for sustained blood sugar control throughout the day.
Uses of Ziglim-M 2 Tablet PR
- Type 2 Diabetes Mellitus
- Long-term blood sugar control
- Reducing the risk of diabetes-related complications when used with a healthy lifestyle
Benefits of Ziglim-M 2 Tablet PR
- Effectively lowers blood glucose levels
- Improves insulin sensitivity
- Reduces glucose production by the liver
- Helps improve long-term HbA1c levels
- Convenient combination therapy in one tablet
How Ziglim-M 2 Tablet PR Works
- Glimepiride stimulates the pancreas to release more insulin, helping lower blood sugar.
- Metformin decreases glucose production by the liver, reduces intestinal glucose absorption, and improves the body’s response to insulin.
Together, these medicines help maintain stable blood sugar levels.
Dosage
- Take Ziglim-M 2 Tablet PR exactly as prescribed by your doctor.
- Swallow the tablet whole with water.
- Do not crush, chew, or break the prolonged-release tablet.
- Continue taking the medicine regularly, even if you feel well.
How to Use
- Take the tablet with food, preferably with breakfast or your first main meal.
- Take it at the same time every day.
- Follow your doctor’s advice regarding diet, exercise, and regular blood sugar monitoring.
Side Effects
Common side effects include:
- Low blood sugar (Hypoglycemia)
- Nausea
- Diarrhea
- Stomach discomfort
- Headache
- Dizziness
Seek immediate medical attention if you develop symptoms of severe hypoglycemia, lactic acidosis (such as unusual weakness, rapid breathing, severe muscle pain), or an allergic reaction.
Precautions
- Not suitable for Type 1 Diabetes Mellitus or diabetic ketoacidosis.
- Inform your doctor if you have kidney disease, liver disease, heart disease, or a history of lactic acidosis.
- Avoid excessive alcohol consumption during treatment.
- Monitor blood sugar levels regularly.
- Consult your doctor before using during pregnancy or breastfeeding.
Drug Interactions
Ziglim-M 2 Tablet PR may interact with:
- Insulin and other anti-diabetic medicines
- Corticosteroids
- Diuretics
- Beta-blockers
- Rifampicin
- Alcohol
- Certain blood pressure medicines
Inform your doctor about all medicines, vitamins, and herbal supplements you are taking.
Storage
- Store below 30°C.
- Protect from moisture and direct sunlight.
- Keep out of reach of children.







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