Itrafix 100 Capsule contains Itraconazole (100mg), a broad-spectrum antifungal used to treat a variety of fungal infections. It works by inhibiting ergosterol synthesis, an essential component of fungal cell membranes, which prevents fungal growth and kills the infection.

This lower-strength capsule is typically prescribed for mild to moderate fungal infections or in long-term maintenance therapy, including skin, nail, and systemic fungal infections.

Uses / Indications

• Dermatophytic infections (ringworm, athlete’s foot, jock itch)

• Onychomycosis (fungal nail infections)

• Yeast infections (candidiasis of skin and mucosa)

• Systemic fungal infections in patients requiring lower-dose therapy

• Maintenance therapy to prevent recurrence in chronic infections

How It Works

• Itraconazole inhibits the fungal enzyme lanosterol 14α-demethylase, which is essential for producing ergosterol.

• Lack of ergosterol weakens fungal cell membranes, stopping growth and leading to cell death.

• Effective against a broad spectrum of yeasts, dermatophytes, and molds.

Dosage & Administration

• Adults: Typically 100mg once or twice daily, depending on infection severity.

• Capsules should be taken after meals to improve absorption.

• Duration may range from 1 week to several months, depending on infection type (e.g., nails may require 3–6 months).

• Always follow doctor’s instructions regarding dose and duration.

Side Effects

Common:

• Nausea, vomiting, or stomach upset

• Diarrhea

• Headache

• Dizziness

Less Common / Rare:

• Rash or itching

• Liver enzyme elevation (requires monitoring)

• Swelling or fluid retention

• Heart issues in patients with pre-existing heart conditions (rare)

Precautions & Warnings

• Not recommended during pregnancy or breastfeeding unless advised by a doctor.

• Caution in patients with liver, heart, or kidney disease.

• Avoid combining with medications that affect liver enzymes or cardiac function.

• Liver function monitoring may be necessary during prolonged therapy.

• Complete the full prescribed course to prevent recurrence or resistance.

Summary

Itrafix 100 Capsule (Itraconazole 100mg) is a safe and effective antifungal for skin, nail, and mild systemic infections. It is particularly useful for long-term therapy or maintenance treatment and should always be taken under medical supervision.

Itrafix 200 Capsule contains Itraconazole (200mg), an antifungal medicine used to treat a wide range of fungal infections. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes, which disrupts fungal growth and kills the infection.

It is commonly prescribed for systemic fungal infections, skin infections, nail infections, and certain fungal lung infections.

Uses / Indications

• Systemic fungal infections (candidiasis, aspergillosis, histoplasmosis)

• Dermatophytic infections (ringworm, athlete’s foot, jock itch)

• Onychomycosis (fungal infections of nails)

• Fungal infections of scalp and skin

• Fungal infections in immunocompromised patients

How It Works

• Itraconazole inhibits the enzyme lanosterol 14α-demethylase, preventing the formation of ergosterol, an essential component of the fungal cell membrane.

• This leads to weakening of the cell membrane, stopping fungal growth and eventually killing the fungus.

• Effective against a broad spectrum of yeasts and dermatophytes.

Dosage & Administration

• Adults: Usually 200mg once or twice daily, depending on the type and severity of infection.

• Capsules should be taken after meals to improve absorption.

• Duration of therapy may vary from 1–3 months or longer for nail and systemic infections.

• Always follow the doctor’s prescribed duration to prevent recurrence or resistance.

Side Effects

Common:

• Nausea, vomiting, or diarrhea

• Stomach discomfort or abdominal pain

• Headache

• Dizziness

Less Common / Rare:

• Rash or itching

• Liver enzyme elevation (monitor liver function during prolonged use)

• Swelling or fluid retention

• Heart failure (rare, in patients with pre-existing heart conditions)

Precautions & Warnings

• Not recommended in pregnancy or breastfeeding unless specifically prescribed.

• Caution in patients with liver disease, heart disease, or kidney impairment.

• Avoid combining with medications that may affect liver enzymes or heart rhythm.

• Regular liver function tests may be required during long-term therapy.

• Complete the full course even if symptoms improve early to prevent recurrence.

Summary

Itrafix 200 Capsule (Itraconazole 200mg) is a broad-spectrum antifungal effective for systemic, skin, nail, and yeast infections. It should be taken under medical supervision with proper monitoring, especially for prolonged treatment, to ensure safety and efficacy.

ITROMED-SB 100 contains itraconazole 100 mg refined with SUBA (SUper-BioAvailable) technology for antifungal therapy. This advanced solid dispersion formula results in higher oral absorption and more consistent blood levels than standard crystalline itraconazole, allowing for lower doses and better tolerability.

SUBA Technology Features

• Enhanced and consistent bioavailability regardless of food, acid, or patient differences

• Therapeutically effective at lower dosages

• Suitable for use in patients with variable GI pH or on acid-reducing medications.

Clinical Uses

• Treatment of fungal infections of skin, oral mucosa (thrush), vagina, nails (onychomycosis), and internal organs.

• Active against dermatophytes, yeasts (Candida), and molds

• Also used for persistent or recurrent fungal infections not responding to conventional therapy

Dosage & Directions

• Take as prescribed, usually with food for optimal absorption; swallow whole.

• Full course should be completed to prevent recurrence

• Not recommended in pregnancy, severe liver disease, heart failure, or with drugs that prolong QT interval

Common Side Effects

• Nausea, vomiting, abdominal pain, headache, dizziness, diarrhea

• Rare: liver toxicity (jaundice), heart rhythm disturbances, allergic reaction

Precautions

• Monitor liver function for long courses

• Avoid antacids within 2 hours of dosing or take with acidic beverages if needed

• Discuss all medications and supplements with healthcare provider

ITROMED-SB 100 is a prescription antifungal with advanced bioavailability, used for a wide range of fungal infections.

ITROMED-SB 65 contains itraconazole 65 mg formulated using SUBA (SUper-BioAvailable) technology. This special pharmaceutical technology enhances bioavailability by using a solid dispersion of itraconazole in a polymer matrix, resulting in superior absorption compared to conventional crystalline itraconazole capsules.

SUBA Technology Benefits

• Enhanced bioavailability: The 65 mg SUBA formulation provides equivalent therapeutic effect to higher doses of conventional itraconazole.

• Consistent absorption: Less dependent on stomach acid and food intake for absorption.

• Reduced variability: More predictable plasma levels between patients and doses.

Uses

• Superficial fungal infections: Ringworm, athlete’s foot, jock itch caused by Trichophyton, Microsporum, and Epidermophyton species.

• Nail infections (onychomycosis): Persistent fungal infections of fingernails and toenails.

• Mucosal candidiasis: Vaginal yeast infections, oral/throat thrush, especially in immunocompromised patients.

• Systemic mycoses: Cryptococcal infections, histoplasmosis, aspergillosis, blastomycosis.

Mechanism of Action

Itraconazole blocks ergosterol synthesis by inhibiting the fungal enzyme lanosterol 14α-demethylase, disrupting the fungal cell membrane and causing cell death.

Common Side Effects

• Nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, constipation, dyspepsia.

• Rare but serious: severe skin reactions, liver toxicity, heart rhythm abnormalities.

Directions & Precautions

• Take with food for optimal absorption.

• Avoid antacids for 2 hours after dosing (or take with cola if antacids necessary).

• Complete full course even if symptoms improve early.

• Monitor liver function for treatments longer than one month.

• Not recommended in pregnancy, heart failure, or severe liver/kidney disease.

ITROMED-SB 65 is a prescription antifungal with enhanced bioavailability technology, widely available in India.

Itrostred SB 65mg Capsule is an antifungal medication used to treat various fungal infections, including skin, nail, and systemic infections. It contains Itraconazole (65mg), which works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This action weakens fungal cells, preventing their growth and helping eliminate infections effectively.

This low-dose formulation is particularly suitable for mild to moderate fungal infections, such as dermatophytic skin infections and nail infections, or for patients requiring long-term maintenance therapy.

Uses:

• Treatment of mild to moderate skin fungal infections (tinea, ringworm, athlete’s foot)

• Nail fungal infections (onychomycosis)

• Systemic fungal infections in lower doses

• Prevention of fungal infections in immunocompromised patients

• Supportive therapy for chronic dermatophytic infections

Key Benefits:

• Effective against superficial and mild systemic fungal infections

• Helps clear skin and nail infections

• Reduces recurrence and supports long-term fungal control

• Convenient low-dose option for maintenance therapy

Directions for Use:
Take Itrostred SB 65mg Capsule orally with a full glass of water, preferably after meals. Swallow the capsule whole; do not crush or chew. Follow your doctor’s dosage and schedule carefully, and complete the full course even if symptoms improve early.

Safety Advice:

• Alcohol: Limit intake to avoid liver strain.

• Pregnancy & Breastfeeding: Consult your doctor before use.

• Liver Disorders: Use with caution; regular liver function monitoring is recommended.

• Drug Interactions: Inform your doctor about all medications to prevent interactions.