Description
Cabergoline 0.5 mg (CABERFORD 0.5) is a dopamine agonist, primarily used to lower high prolactin levels in the blood (hyperprolactinemia).
Uses / Indications
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Hyperprolactinemia: Treats high levels of prolactin, which may cause infertility, irregular menstruation, and abnormal milk production (galactorrhea) in women, and sexual dysfunction or infertility in men.
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Suppression of lactation: Used when there is a medical need to stop or prevent breast milk production after childbirth, miscarriage, stillbirth, or abortion.
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Prolactin-secreting pituitary tumors: Used in prolactinomas to shrink tumors and reduce hormone levels.
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Adjunct for disorders like acromegaly and less commonly for Parkinson’s disease (now rare due to safer alternatives).
How it Works
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Stimulates dopamine D2 receptors, directly inhibiting prolactin secretion from the pituitary gland, normalizing menstruation and fertility, and reducing tumor size when present.
Dosage & Administration
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Typically, 0.25–0.5 mg per week in 1–2 divided doses, titrated by your doctor based on prolactin response.
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May be gradually increased up to 1–2 mg/week if needed, with blood prolactin monitoring.
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Take with or without food; do not stop suddenly without doctor guidance.
Safety & Side Effects
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Common: nausea, dizziness, headache, weakness, tiredness, stomach pain, constipation, sleepiness, low blood pressure.
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Rare/serious: hallucinations, heart valve changes (especially at higher/long-term doses), depression, impulse control changes—seek prompt medical attention if these occur.
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Contraindications: allergy to cabergoline/ergots, severe liver impairment, history of heart valve disease, psychiatric disorders, or severe hypertension in pregnancy.
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Not for use in children; caution in elderly and in those with other medical problems.
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Monitoring: Periodic heart valve checks and prolactin levels may be advised.
Note:
Always follow your doctor’s instructions. Do not self-adjust dose or stop abruptly—sudden withdrawal can cause hormone rebound. Keep your clinician informed of all other medicines and health changes.







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