Okamet GMP 2 Tablet is a triple-drug oral antidiabetic formulation manufactured by Cipla Ltd. It contains Glimepiride 2mg, Metformin Hydrochloride 500mg (Sustained Release), and Pioglitazone 15mg. This medicine is prescribed to patients with Type 2 Diabetes Mellitus whose blood glucose is not adequately controlled with dual therapy or lifestyle modifications alone.
It provides comprehensive glycemic control by targeting different pathways responsible for high blood sugar, making it highly effective for long-term diabetes management.
How Okamet GMP 2 Works
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Glimepiride (2mg): A sulfonylurea that stimulates the pancreas to release more insulin, thereby reducing high blood sugar after meals.
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Metformin SR (500mg): A biguanide that lowers glucose production in the liver, delays intestinal absorption of sugar, and improves insulin sensitivity.
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Pioglitazone (15mg): A thiazolidinedione that enhances the body’s response to insulin and improves glucose uptake in muscles and fat tissues.
This three-way mechanism ensures effective control of both fasting and postprandial (after-meal) blood glucose levels.
Uses of Okamet GMP 2 Tablet
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Management of Type 2 Diabetes Mellitus in adults.
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Helps control fasting and post-meal blood sugar levels.
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Prevents the risk of diabetes-related complications such as:
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Neuropathy (nerve damage)
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Nephropathy (kidney damage)
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Retinopathy (eye damage)
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Cardiovascular complications (heart disease, stroke).
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Useful for patients needing triple-drug therapy when single or dual drug therapy is not enough.
Dosage & Administration
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Usually taken once daily with a meal (preferably breakfast or as directed by doctor).
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Swallow whole with water; do not crush or chew.
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Dose is individualized based on blood glucose levels and patient’s response.
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Regular monitoring of blood sugar, HbA1c, kidney, and liver function is essential.
Precautions
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Not for Type 1 Diabetes or diabetic ketoacidosis.
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Caution in patients with heart failure, kidney or liver impairment.
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Avoid alcohol (increases risk of lactic acidosis and hypoglycemia).
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May cause weight gain and fluid retention (due to Pioglitazone).
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Not recommended during pregnancy or breastfeeding unless advised by a doctor.
Possible Side Effects
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Hypoglycemia (sweating, tremors, dizziness, weakness, hunger)
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Gastrointestinal upset: nausea, vomiting, diarrhea (from Metformin)
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Weight gain, fluid retention, ankle swelling (from Pioglitazone)
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Headache or dizziness
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Rare but serious: Lactic acidosis, liver dysfunction, or worsening of heart failure
Overall Benefit
Okamet GMP 2 Tablet provides a powerful triple-action therapy for effective control of Type 2 Diabetes. By combining Glimepiride, Metformin SR, and Pioglitazone, it helps achieve stable blood sugar control, reduces long-term diabetes complications, and improves the overall quality of life for patients needing intensive management.
Olmezest 20 Tablet is a prescription medicine used for the management of high blood pressure (hypertension). It contains Olmesartan Medoxomil (20mg), an angiotensin II receptor blocker (ARB) that relaxes blood vessels, lowers blood pressure, and improves blood flow, reducing the risk of heart attack, stroke, and kidney damage.
Uses:
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Treatment of hypertension to lower elevated blood pressure
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Reduces risk of cardiovascular complications in patients with high blood pressure
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Helps protect kidneys in patients with type 2 diabetes and hypertension
How to Use:
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Take the tablet orally as prescribed by your doctor, usually once daily.
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Can be taken with or without food.
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Swallow whole with water.
Dosage:
Precautions:
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Inform your doctor if you have kidney disease, liver disease, or heart problems.
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Avoid potassium supplements or salt substitutes containing potassium unless prescribed.
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Use with caution during pregnancy and breastfeeding.
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Monitor blood pressure regularly.
Possible Side Effects:
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Dizziness, headache, or fatigue
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Mild gastrointestinal discomfort
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Rare: severe allergic reactions, kidney impairment, or low blood pressure
Oxra 10mg Tablet contains Dapagliflozin (10mg), a medicine belonging to the class of sodium-glucose co-transporter-2 (SGLT2) inhibitors. It is primarily used to manage type 2 diabetes mellitus by lowering high blood sugar levels. It works by helping the kidneys remove excess glucose from the bloodstream through urine. Apart from controlling blood sugar, it may also provide benefits in reducing the risk of heart failure and protecting kidney health in diabetic patients.
Uses:
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Management of type 2 diabetes mellitus
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Helps reduce risk of hospitalization for heart failure in diabetic patients
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May help in protecting kidney function in chronic kidney disease
How to Use:
Take the tablet as advised by your doctor, usually once daily. Swallow whole with water, with or without food. Maintain a proper diet and exercise routine along with this medicine.
Dosage:
The dose depends on your health condition, blood sugar levels, and response to treatment. Do not stop or change the dose without consulting your doctor.
Precautions:
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Not recommended for type 1 diabetes or diabetic ketoacidosis.
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Inform your doctor if you have kidney, liver, or urinary tract problems.
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Maintain proper hydration as this medicine increases urine output.
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Use with caution during pregnancy and breastfeeding.
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Monitor blood sugar regularly.
Side Effects:
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Frequent urination, increased thirst
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Low blood sugar (when combined with other anti-diabetic medicines)
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Urinary tract infections, genital infections
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Dizziness, dehydration
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Low blood pressure in some patients
Oxra 5mg Tablet contains Dapagliflozin (5mg), an SGLT2 (sodium-glucose co-transporter-2) inhibitor used for the management of type 2 diabetes mellitus. It works by promoting the removal of excess glucose from the body through urine, thereby lowering blood sugar levels. This medicine, when combined with proper diet and exercise, helps improve glycemic control and may also reduce the risk of heart failure and kidney complications in diabetic patients.
Uses:
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Management of type 2 diabetes mellitus
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May reduce the risk of heart failure hospitalization in diabetic patients
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Offers kidney protection in certain chronic kidney disease patients
How to Use:
Take the tablet once daily as prescribed by your doctor. Swallow it whole with water, with or without food. Follow your recommended diet and exercise plan for best results.
Dosage:
The dosage depends on your blood sugar levels, health condition, and response to treatment. Do not alter or discontinue the dose without medical advice.
Precautions:
-
Not suitable for type 1 diabetes or diabetic ketoacidosis.
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Inform your doctor if you have kidney or liver problems.
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Maintain proper fluid intake to avoid dehydration.
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Use with caution during pregnancy and breastfeeding.
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Monitor your blood sugar levels regularly.
Side Effects:
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Increased urination, excessive thirst
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Urinary tract infections, genital infections
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Low blood sugar (especially with insulin or other diabetes medicines)
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Dizziness, dehydration
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Low blood pressure in some cases
Oxra S 10mg/100mg Tablet is a combination of Dapagliflozin (10mg) and Sitagliptin (100mg), used for the effective management of type 2 diabetes mellitus. This dual therapy helps improve blood sugar control when diet, exercise, and single-agent treatment are not sufficient.
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Dapagliflozin is an SGLT2 inhibitor that lowers blood sugar by removing excess glucose through urine.
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Sitagliptin is a DPP-4 inhibitor that increases incretin hormone levels, boosting insulin release and reducing sugar production by the liver.
Together, they work in different ways to help maintain stable blood glucose levels and reduce the risk of diabetes-related complications.
Uses:
-
Management of type 2 diabetes mellitus
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Helps achieve better glycemic control when monotherapy is inadequate
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May provide additional heart and kidney protection in diabetic patients
How to Use:
Take the tablet exactly as prescribed by your doctor, usually once daily. Swallow it whole with water, with or without food. Continue with your recommended diet and exercise plan for maximum benefit.
Dosage:
The dosage is individualized based on blood sugar levels, health condition, and prior response to diabetes medicines. Do not skip or stop without consulting your doctor.
Precautions:
-
Not for use in type 1 diabetes or diabetic ketoacidosis.
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Inform your doctor if you have kidney, liver, or heart problems.
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Stay hydrated as dapagliflozin may cause increased urination.
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May increase risk of urinary tract and genital infections.
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Use cautiously in pregnancy and breastfeeding.
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Regularly monitor blood sugar, kidney function, and HbA1c.
Side Effects:
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Urinary tract infections, genital infections
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Headache, sore throat, stuffy nose
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Increased urination, dehydration
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Low blood sugar (especially with insulin or sulfonylureas)
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Nausea, stomach pain
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Rarely, pancreatitis or allergic reactions
Oxra S 5mg/100mg Tablet is a combination medicine containing Dapagliflozin (5mg) and Sitagliptin (100mg), prescribed for the treatment of type 2 diabetes mellitus. It helps in lowering blood glucose levels when lifestyle changes and single-drug therapy are not enough.
-
Dapagliflozin is an SGLT2 inhibitor that helps the kidneys remove excess glucose from the blood through urine.
-
Sitagliptin is a DPP-4 inhibitor that enhances incretin activity, leading to increased insulin release and decreased sugar production by the liver.
Together, they provide better blood sugar control and may also reduce risks of heart and kidney complications in diabetes.
Uses:
-
Management of type 2 diabetes mellitus
-
Helps in achieving better control of blood sugar when monotherapy is insufficient
-
May reduce risk of cardiovascular and kidney-related complications in diabetic patients
How to Use:
Take the tablet once daily or as directed by your doctor. Swallow whole with water, with or without food. Follow a proper diet and exercise plan along with medication.
Dosage:
The dose is decided by your doctor based on your blood sugar levels and medical condition. Do not self-adjust the dose or discontinue suddenly.
Precautions:
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Not recommended in type 1 diabetes or diabetic ketoacidosis.
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Inform your doctor if you have kidney, liver, or heart disease.
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May increase risk of urinary and genital infections; maintain good personal hygiene.
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Stay well hydrated to avoid dehydration.
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Use with caution during pregnancy and breastfeeding.
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Monitor blood sugar and kidney function regularly.
Side Effects:
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Urinary tract infections, genital infections
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Increased urination, dehydration
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Headache, sore throat, nasal congestion
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Nausea, stomach upset
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Low blood sugar when combined with insulin or other anti-diabetics
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Rarely, pancreatitis or allergic reactions
Oxramet 5mg/1000mg Tablet IR is a combination of Dapagliflozin (5mg) and Metformin (1000mg), used in the management of type 2 diabetes mellitus. This dual therapy helps control blood sugar levels more effectively when diet, exercise, and single-drug therapy are not enough.
-
Dapagliflozin is an SGLT2 inhibitor that helps the kidneys eliminate excess glucose through urine, thereby lowering blood sugar.
-
Metformin is a biguanide that reduces glucose production in the liver and improves insulin sensitivity, helping the body use insulin more effectively.
Together, they provide stronger blood sugar control and may also reduce the risk of cardiovascular and kidney complications related to diabetes.
Uses:
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Treatment of type 2 diabetes mellitus
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Helps reduce blood sugar when single therapy is inadequate
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May support weight management and improve heart & kidney outcomes in diabetic patients
How to Use:
Take the tablet with meals to minimize stomach upset, exactly as prescribed by your doctor. Swallow whole with water. Continue diet control and regular exercise along with the medication.
Dosage:
The dosage is tailored by your doctor depending on your blood sugar levels, response to treatment, and overall health. Do not skip or stop the medicine without medical advice.
Precautions:
-
Not recommended in type 1 diabetes or diabetic ketoacidosis.
-
Inform your doctor if you have kidney, liver, or heart disease.
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Metformin may cause lactic acidosis (rare but serious); report symptoms like muscle pain, breathing trouble, or severe weakness immediately.
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Dapagliflozin may increase the risk of urinary tract and genital infections.
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Stay hydrated to prevent dehydration.
-
Use cautiously in pregnancy and breastfeeding.
-
Regular monitoring of blood sugar, kidney function, and vitamin B12 levels is advised.
Side Effects:
-
Nausea, vomiting, diarrhea, stomach upset (due to Metformin)
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Increased urination, urinary tract infections, genital infections (due to Dapagliflozin)
-
Low blood sugar when used with insulin or sulfonylureas
-
Dizziness, dehydration
-
Rare: lactic acidosis, severe allergic reactions
Oxramet 5mg/1000mg Tablet IR is a combination medicine containing Dapagliflozin (5mg) and Metformin (1000mg), prescribed for the management of type 2 diabetes mellitus. It helps in lowering high blood sugar levels, especially in patients where diet, exercise, and single-drug therapy are insufficient.
-
Dapagliflozin (SGLT2 inhibitor) works by removing excess glucose from the body through urine.
-
Metformin (biguanide) decreases glucose production in the liver and improves the body’s response to insulin.
This combination helps achieve better blood sugar control, reduces the risk of diabetes-related complications, and may also support weight management and heart protection.
Uses:
-
Management of type 2 diabetes mellitus
-
Helps improve blood sugar control when monotherapy is inadequate
-
May lower the risk of cardiovascular and kidney complications in diabetic patients
How to Use:
Take the tablet with meals to reduce stomach discomfort. Swallow it whole with water. Follow your doctor’s advice regarding diet and exercise along with this medicine.
Dosage:
Dosage is individualized depending on your blood sugar levels, response, and overall health. Do not miss doses or stop treatment without consulting your doctor.
Precautions:
-
Not suitable for type 1 diabetes or diabetic ketoacidosis.
-
Inform your doctor if you have kidney, liver, or heart problems.
-
Metformin may rarely cause lactic acidosis; seek medical attention if you experience unexplained muscle pain, shortness of breath, or severe weakness.
-
Dapagliflozin may increase the risk of urinary tract or genital infections.
-
Maintain proper hydration to avoid dehydration.
-
Use cautiously during pregnancy and breastfeeding.
-
Regular monitoring of blood sugar, kidney function, and vitamin B12 levels is recommended.
Side Effects:
-
Nausea, vomiting, diarrhea, stomach upset (Metformin-related)
-
Increased urination, urinary tract infections, genital infections (Dapagliflozin-related)
-
Low blood sugar when taken with insulin or sulfonylureas
-
Dizziness, dehydration
-
Rare but serious: lactic acidosis, severe allergic reactions
Oxramet 5mg/500mg Tablet IR is a combination of Dapagliflozin (5mg) and Metformin (500mg), used for the management of type 2 diabetes mellitus. It is prescribed when diet, exercise, and single-drug treatment do not provide adequate blood sugar control.
-
Dapagliflozin is an SGLT2 inhibitor that reduces blood sugar by removing excess glucose from the body through urine.
-
Metformin is a biguanide that decreases glucose production in the liver and enhances the body’s sensitivity to insulin.
This dual therapy helps achieve better glycemic control, reduces the risk of long-term diabetes complications, and may also provide additional benefits for heart and kidney health.
Uses:
-
Treatment of type 2 diabetes mellitus
-
Improves blood sugar control when monotherapy is inadequate
-
May reduce risk of cardiovascular and kidney-related complications in diabetic patients
How to Use:
Take the tablet with meals to minimize stomach irritation. Swallow it whole with water. Always follow your doctor’s advice on diet and lifestyle along with medication.
Dosage:
The dose depends on your blood sugar levels, overall health, and doctor’s recommendations. Do not self-adjust or discontinue the medicine without medical supervision.
Precautions:
-
Not intended for type 1 diabetes or diabetic ketoacidosis.
-
Inform your doctor if you have kidney, liver, or heart problems.
-
Metformin may rarely cause lactic acidosis; seek urgent care if you experience unusual tiredness, muscle pain, or breathing difficulty.
-
Dapagliflozin may increase the risk of urinary tract and genital infections.
-
Stay hydrated to avoid dehydration.
-
Use cautiously during pregnancy and breastfeeding.
-
Regular monitoring of blood sugar, kidney function, and vitamin B12 levels is recommended.
Side Effects:
-
Nausea, diarrhea, abdominal pain (Metformin-related)
-
Increased urination, urinary or genital infections (Dapagliflozin-related)
-
Low blood sugar when combined with insulin or other diabetes medicines
-
Dizziness, dehydration
-
Rare but serious: lactic acidosis, severe allergic reactions
Oxramet XR 10mg/1000mg Tablet is a combination of Dapagliflozin (10mg) and Metformin (1000mg) in an extended-release (XR) formulation, prescribed for the management of type 2 diabetes mellitus. It helps achieve better control of blood sugar levels, especially in patients not adequately managed with diet, exercise, or monotherapy.
-
Dapagliflozin (SGLT2 inhibitor) works by removing excess glucose from the body through urine.
-
Metformin XR (biguanide, extended-release) reduces glucose production in the liver, improves insulin sensitivity, and provides longer-lasting control with fewer gastrointestinal side effects compared to immediate-release.
This combination helps reduce high blood sugar, lowers the risk of long-term complications of diabetes, and may also provide benefits for heart and kidney health.
Uses:
-
Management of type 2 diabetes mellitus
-
Improves glycemic control when diet, exercise, or single therapy is insufficient
-
May lower the risk of cardiovascular and kidney complications in diabetic patients
How to Use:
Take the tablet once daily with meals, preferably in the evening, to minimize stomach upset. Swallow whole with water; do not crush or chew. Follow your doctor’s advice regarding diet and exercise.
Dosage:
Dosage is personalized depending on your blood sugar levels, overall health, and treatment response. Do not skip or stop the medication without consulting your doctor.
Precautions:
-
Not suitable for type 1 diabetes or diabetic ketoacidosis.
-
Inform your doctor if you have kidney, liver, or heart disease.
-
Metformin (XR) may rarely cause lactic acidosis; seek urgent care for symptoms like severe weakness, muscle pain, or breathing difficulty.
-
Dapagliflozin may increase the risk of urinary tract and genital infections.
-
Maintain adequate hydration to avoid dehydration.
-
Use with caution during pregnancy and breastfeeding.
-
Regular monitoring of blood sugar, kidney function, and vitamin B12 levels is recommended.
Side Effects:
-
Nausea, diarrhea, abdominal discomfort (less common in XR form)
-
Increased urination, urinary tract infections, genital infections
-
Low blood sugar when used with insulin or sulfonylureas
-
Dizziness, dehydration
-
Rare: lactic acidosis, severe allergic reactions
Oxramet XR 10mg/500mg Tablet is a combination of Dapagliflozin (10mg) and Metformin (500mg) in an extended-release (XR) formulation, used for the management of type 2 diabetes mellitus. It is prescribed when diet, exercise, and single-drug therapy are not sufficient to control blood sugar levels.
-
Dapagliflozin is an SGLT2 inhibitor that lowers blood sugar by helping the kidneys eliminate excess glucose through urine.
-
Metformin XR is a biguanide that reduces glucose production in the liver, improves insulin sensitivity, and offers sustained blood sugar control with fewer stomach-related side effects compared to immediate-release.
Together, they provide better glycemic control, reduce the risk of long-term diabetes complications, and may also support heart and kidney health.
Uses:
-
Treatment of type 2 diabetes mellitus
-
Improves glycemic control when monotherapy is inadequate
-
May help reduce the risk of cardiovascular and kidney-related complications
How to Use:
Take the tablet once daily with meals, preferably in the evening, to minimize gastrointestinal side effects. Swallow whole with water; do not crush or chew. Follow your doctor’s advice on diet and exercise along with the medicine.
Dosage:
The dosage is individualized by the doctor based on your blood sugar levels, health condition, and treatment response. Do not stop or alter the dose without medical supervision.
Precautions:
-
Not recommended for type 1 diabetes or diabetic ketoacidosis.
-
Inform your doctor if you have kidney, liver, or heart disease.
-
Metformin XR may rarely cause lactic acidosis; seek urgent help if you experience unusual tiredness, breathing difficulty, or severe weakness.
-
Dapagliflozin may increase the risk of urinary tract or genital infections.
-
Maintain adequate hydration to avoid dehydration.
-
Use cautiously during pregnancy and breastfeeding.
-
Regular monitoring of blood sugar, kidney function, and vitamin B12 levels is advised.
Side Effects:
-
Stomach upset, nausea, diarrhea (less frequent with XR form)
-
Increased urination, urinary tract infections, genital infections
-
Dizziness, dehydration
-
Low blood sugar when combined with insulin or sulfonylureas
-
Rare: lactic acidosis, severe allergic reactions
About Pevesca Plus Capsule:
Pevesca Plus Capsule combines Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin, and Vitamin B6 to provide comprehensive nerve support. It is commonly prescribed for peripheral neuropathy caused by diabetes, chemotherapy, or nerve injury, addressing nerve damage, pain, and vitamin deficiencies simultaneously.
How It Works:
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Alpha Lipoic Acid: Antioxidant that reduces oxidative stress and supports nerve regeneration.
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Methylcobalamin (Vitamin B12): Essential for nerve repair and myelin sheath maintenance.
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Folic Acid & Vitamin B6: Support nerve function and metabolism.
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Pregabalin: Modulates nerve signaling to reduce neuropathic pain.
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The combination provides symptomatic relief and promotes nerve recovery.
Uses:
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Management of diabetic or peripheral neuropathy
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Relief from nerve pain, tingling, and numbness
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Supports nerve repair and vitamin supplementation
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Suitable for patients with vitamin B deficiencies contributing to neuropathy
Directions for Use:
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Take once or twice daily as prescribed by a doctor.
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Swallow the capsule whole with water, preferably after meals.
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Follow a balanced diet and healthy lifestyle for optimal nerve health.
Side Effects:
Common side effects may include:
Seek medical attention if you experience severe dizziness, swelling, or signs of allergic reaction.
Precautions:
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Use with caution in patients with kidney or liver impairment
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Avoid alcohol while taking this medication as it may worsen drowsiness or neuropathic symptoms
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Not recommended during pregnancy or breastfeeding unless prescribed
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Regular monitoring of nerve function and vitamin levels is advised
